Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 130497
Gene Symbol: OSR1
OSR1 		0.010 Biomarker group BEFREE Childhood ADHD, ODD, CD, and depression increase the risk of developing substance-related disorders. 28647007 2017
Entrez Id: 288
Gene Symbol: ANK3
ANK3 		0.010 Biomarker group BEFREE This led us to hypothesize that ANK3 might also be associated with stress-related psychopathology such as posttraumatic stress disorder (PTSD), as well as disorders of the externalizing spectrum such as antisocial personality disorder and substance-related disorders that are etiologically linked to impulsivity and temperamental disinhibition. 23796624 2013
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B 		0.010 GeneticVariation group LHGDN The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse. 15608559 2004
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.020 GeneticVariation group BEFREE The brain derived neurotrophic factor (BDNF) locus has been implicated in psychiatric and substance related disorders. 23624487 2013
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.020 Biomarker group LHGDN Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia. 17217930 2007
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B 		0.100 GeneticVariation group GWASCAT KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. 26202629 2016
Entrez Id: 23114
Gene Symbol: NFASC
NFASC 		0.100 GeneticVariation group GWASCAT NCK2 is significantly associated with opiates addiction in African-origin men. 23533358 2013
Entrez Id: 8440
Gene Symbol: NCK2
NCK2 		0.100 GeneticVariation group GWASCAT NCK2 is significantly associated with opiates addiction in African-origin men. 23533358 2013
Entrez Id: 63876
Gene Symbol: PKNOX2
PKNOX2 		0.100 GeneticVariation group GWASCAT The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women. 21298047 2011
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.200 Therapeutic group RGD Glycogen synthase kinase 3 beta regulates ethanol consumption and is a risk factor for alcohol dependence. 30188517 2018
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2 		0.200 Biomarker group RGD A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine. 17683483 2007
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C 		0.200 Biomarker group RGD Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. 16474401 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.200 Biomarker group RGD Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. 16474401 2006
Entrez Id: 356
Gene Symbol: FASLG
FASLG 		0.200 Biomarker group RGD Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. 15644446 2005
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1 		0.300 Biomarker group CTD_human Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators. 27192616 2016
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		0.300 Biomarker group CTD_human Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. 21513772 2011
Entrez Id: 114788
Gene Symbol: CSMD3
CSMD3 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 1962
Gene Symbol: EHHADH
EHHADH 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9271
Gene Symbol: PIWIL1
PIWIL1 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 5583
Gene Symbol: PRKCH
PRKCH 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 64131
Gene Symbol: XYLT1
XYLT1 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 55742
Gene Symbol: PARVA
PARVA 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 1826
Gene Symbol: DSCAM
DSCAM 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9128
Gene Symbol: PRPF4
PRPF4 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 57733
Gene Symbol: GBA3
GBA3 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010