Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1 		0.100 Biomarker phenotype HPO
Entrez Id: 1639
Gene Symbol: DCTN1
DCTN1 		0.100 Biomarker phenotype HPO
Entrez Id: 2896
Gene Symbol: GRN
GRN 		0.100 Biomarker phenotype HPO
Entrez Id: 23230
Gene Symbol: VPS13A
VPS13A 		0.100 Biomarker phenotype HPO
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B 		0.100 Biomarker phenotype HPO
Entrez Id: 8398
Gene Symbol: PLA2G6
PLA2G6 		0.100 Biomarker phenotype HPO
Entrez Id: 57338
Gene Symbol: JPH3
JPH3 		0.100 Biomarker phenotype HPO
Entrez Id: 54476
Gene Symbol: RNF216
RNF216 		0.100 Biomarker phenotype HPO
Entrez Id: 2629
Gene Symbol: GBA
GBA 		0.100 Biomarker phenotype HPO
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		0.100 Biomarker phenotype HPO
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.100 Biomarker phenotype HPO
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		0.100 GeneticVariation phenotype CLINVAR
Entrez Id: 7415
Gene Symbol: VCP
VCP 		0.100 Biomarker phenotype HPO
Entrez Id: 10908
Gene Symbol: PNPLA6
PNPLA6 		0.100 Biomarker phenotype HPO
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		0.100 Biomarker phenotype HPO
Entrez Id: 8891
Gene Symbol: EIF2B3
EIF2B3 		0.100 Biomarker phenotype HPO
Entrez Id: 6315
Gene Symbol: ATXN8OS
ATXN8OS 		0.100 Biomarker phenotype HPO
Entrez Id: 1967
Gene Symbol: EIF2B1
EIF2B1 		0.100 Biomarker phenotype HPO
Entrez Id: 54664
Gene Symbol: TMEM106B
TMEM106B 		0.100 Biomarker phenotype HPO
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		0.100 Biomarker phenotype HPO
Entrez Id: 4001
Gene Symbol: LMNB1
LMNB1 		0.100 Biomarker phenotype HPO
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.020 Biomarker phenotype BEFREE A similar phenomenon may be the early personality changes and frontotemporal atrophy in patients with SNCA multiplication. 22166445 2012
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		0.020 Biomarker phenotype BEFREE In conclusion, (1) a frontal lobe syndrome-like personality change may be one of the characteristic clinical features of early-onset CWP-AD, (2) the deposition pattern of Abeta40 and Abeta42 in CWP-AD is more variable than that of presenilin-1-linked cases, (3) Abeta deposition can result in development of dementia without tau pathology, and (4) CWP-AD with LBs and several other neurodegenerative disorders with LBs share a common process involving alpha-synuclein and NAC deposition. 12883830 2003
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.010 GeneticVariation phenotype BEFREE The new sample suggested that personality changes were larger in individuals taking cognition-enhancing medications (cholinesterase inhibitors or memantine). 30630729 2019
Entrez Id: 4340
Gene Symbol: MOG
MOG 		0.010 Biomarker phenotype BEFREE Atypical presentation of MOG-related disease: Slowly progressive behavioral and personality changes following a seizure. 31525625 2019