×
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.020
Biomarker
disease
BEFREE
(1) To determine the serum levels of vitamin D, calcium and C-reactive protein (CRP ) in patients with psoriasis vulgaris , (2) To compare these levels with the serum levels of controls, and (3) To correlate them with the severity of the disease.
29937564 2019
×
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
0.060
GeneticVariation
disease
BEFREE
(ii) HLA-A *26-B*27 [P < 0.0001, odds ratio (OR) = 48.38], -A*26-Cw*0602 (P < 0.0001, OR = 11.84), -B*27-Cw*0602 (P < 0.0001, OR = undefined), -DRB1*0701/02-B*27 (P < 0.0001, OR = 22.62), -DRB1*0701/02-DQA1*0104 (P < 0.0002, OR = 3.59), -DRB1*0701/02-DQB1*0303 (P < 0.0001, OR = 5.63), -DQA1*0201-DQB1*0303 (P < 0.0002, OR = 7.77), -A*26-B*27-Cw*0602 (P < 0.0004, OR = undefined), -A*26-DRB1*0701/02-DQA1*0201-DQB1*0303 (P < 0.01, OR = undefined) were identified as risk haplotypes for patients with PV in China.
15245541 2004
HLA-DRB1
0.070
GeneticVariation
disease
BEFREE
(ii) HLA-A*26-B*27 [P < 0.0001, odds ratio (OR) = 48.38], -A*26-Cw*0602 (P < 0.0001, OR = 11.84), -B*27-Cw*0602 (P < 0.0001, OR = undefined), -DRB1 *0701/02-B*27 (P < 0.0001, OR = 22.62), -DRB1 *0701/02-DQA1*0104 (P < 0.0002, OR = 3.59), -DRB1 *0701/02-DQB1*0303 (P < 0.0001, OR = 5.63), -DQA1*0201-DQB1*0303 (P < 0.0002, OR = 7.77), -A*26-B*27-Cw*0602 (P < 0.0004, OR = undefined), -A*26-DRB1 *0701/02-DQA1*0201-DQB1*0303 (P < 0.01, OR = undefined) were identified as risk haplotypes for patients with PV in China.
15245541 2004
×
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.050
GeneticVariation
disease
BEFREE
(ii) HLA-A*26-B*27 [P < 0.0001, odds ratio (OR) = 48.38], -A*26-Cw*0602 (P < 0.0001, OR = 11.84), -B*27-Cw*0602 (P < 0.0001, OR = undefined), -DRB1 *0701/02-B*27 (P < 0.0001, OR = 22.62), -DRB1 *0701/02-DQA1*0104 (P < 0.0002, OR = 3.59), -DRB1 *0701/02-DQB1*0303 (P < 0.0001, OR = 5.63), -DQA1*0201-DQB1*0303 (P < 0.0002, OR = 7.77), -A*26-B*27-Cw*0602 (P < 0.0004, OR = undefined), -A*26-DRB1 *0701/02-DQA1*0201-DQB1*0303 (P < 0.01, OR = undefined) were identified as risk haplotypes for patients with PV in China.
15245541 2004
HLA-DQA1
0.060
GeneticVariation
disease
BEFREE
(ii) HLA-A*26-B*27 [P < 0.0001, odds ratio (OR) = 48.38], -A*26-Cw*0602 (P < 0.0001, OR = 11.84), -B*27-Cw*0602 (P < 0.0001, OR = undefined), -DRB1*0701/02-B*27 (P < 0.0001, OR = 22.62), -DRB1*0701/02-DQA1 *0104 (P < 0.0002, OR = 3.59), -DRB1*0701/02-DQB1*0303 (P < 0.0001, OR = 5.63), -DQA1 *0201-DQB1*0303 (P < 0.0002, OR = 7.77), -A*26-B*27-Cw*0602 (P < 0.0004, OR = undefined), -A*26-DRB1*0701/02-DQA1 *0201-DQB1*0303 (P < 0.01, OR = undefined) were identified as risk haplotypes for patients with PV in China.
15245541 2004
×
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
0.100
GeneticVariation
disease
BEFREE
Psoriasis vulgaris and psoriatic arthritis share a 100 kb susceptibility region telomeric to HLA-C .12730526 2003
×
Entrez Id: 50616
Gene Symbol: IL22
IL22
0.020
Biomarker
disease
BEFREE
Psoriasis vulgaris is an inflammatory skin disease mediated by Th1 and Th17 cytokines, yet the relative contribution of interferon (IFN)-gamma, interleukin (IL)-17 and IL-22 on disease pathogenesis is still unknown.18684158 2008
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
0.010
Biomarker
disease
BEFREE
Psoriasis vulgaris concurrence was lowest in PPP (15.8% vs 54.4% in GPP and 46.2% in ACH , P < .0005 for both), whereas the mean age of onset was earliest in GPP (31.0 vs 43.7 years in PPP and 51.8 years in ACH , P < .0001 for both).30036598 2019
×
Entrez Id: 1041
Gene Symbol: CDSN
CDSN
0.060
AlteredExpression
disease
BEFREE
Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders.11454986 2001
×
Entrez Id: 432355
Gene Symbol: SLURP2
SLURP2
0.010
AlteredExpression
disease
BEFREE
SLURP-2 , a novel member of the human Ly-6 superfamily that is up-regulated in psoriasis vulgaris .12573258 2003
×
Entrez Id: 66004
Gene Symbol: LYNX1
LYNX1
0.010
AlteredExpression
disease
BEFREE
SLURP-2 , a novel member of the human Ly-6 superfamily that is up-regulated in psoriasis vulgaris .12573258 2003
LYNX1-SLURP2
0.010
AlteredExpression
disease
BEFREE
SLURP-2 , a novel member of the human Ly-6 superfamily that is up-regulated in psoriasis vulgaris .12573258 2003
×
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
0.100
GeneticVariation
disease
BEFREE
HLA-Cw *0304 (5.07% vs. 14.43%, Pc < 1 x 10(-3)), -DQA1*0501 (5.79% vs. 14.09%, Pc < 0.05) were found to be negatively associated with PV , but HLA-A*2 (2.54% vs. 6.38%, Pc < 0.5) was decreased in PV patients without statistical significance.15245541 2004
×
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
0.100
GeneticVariation
disease
BEFREE
PSORS1 is the major susceptibility locus for psoriasis vulgaris (PV ) and lies within an approximately 200 kb segment of the major histocompatibility complex on chromosome 6p21.3.15654960 2005
×
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
0.100
GeneticVariation
disease
BEFREE
PSORS1 on chromosome 6p21.3, which contains the MHC , is a major susceptibility locus for psoriasis vulgaris .15953084 2005
×
Entrez Id: 5432
Gene Symbol: POLR2C
POLR2C
0.010
Biomarker
disease
BEFREE
RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product.16141233 2005
×
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.030
Biomarker
disease
BEFREE
HCR , previously identified as alpha-helix coiled-coil rod homologue, is one of the psoriasis vulgaris (PV ) candidate genes.16141233 2005
×
Entrez Id: 9034
Gene Symbol: CCRL2
CCRL2
0.030
Biomarker
disease
BEFREE
HCR , previously identified as alpha-helix coiled-coil rod homologue, is one of the psoriasis vulgaris (PV ) candidate genes.16141233 2005
×
Entrez Id: 27102
Gene Symbol: EIF2AK1
EIF2AK1
0.030
Biomarker
disease
BEFREE
HCR , previously identified as alpha-helix coiled-coil rod homologue, is one of the psoriasis vulgaris (PV ) candidate genes.16141233 2005
×
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.030
Biomarker
disease
BEFREE
CTLA-4 gene polymorphisms and natural soluble CTLA-4 protein in psoriasis vulgaris .16712655 2006
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.020
GeneticVariation
disease
BEFREE
TGF-beta(1 ) gene polymorphism in codon 10 and 25 is not associated with susceptibility to psoriasis vulgaris , but may be important for the type of the disease.17560118 2007
×
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.020
GeneticVariation
disease
BEFREE
IFN-gamma promoter gene polymorphism in psoriasis vulgaris .17852079 2008
×
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
0.100
Biomarker
disease
BEFREE
HLA-C is firmly established as a PsV /PsA gene, with HLA-Cw *0602 as a major risk allele.22298274 2012
×
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
0.010
Biomarker
disease
BEFREE
RUNX-3 is involved in CD8+ T lymphocyte differentiation and is therefore a good candidate for involvement in PsA and psoriasis vulgaris as T cell-mediated diseases.23401011 2013
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100
Biomarker
disease
BEFREE
TNF -like ligand 1A is associated with the pathogenesis of psoriasis vulgaris and contributes to IL-17 production in PBMCs.25200589 2014