| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | group | BEFREE | Patients with TID had significantly higher values of α-1-m and NAG, with lower values of albumin and IgG in the urine compared to patients with GLOM. | 28601117 | 2018 | ||||
|
0.080 | AlteredExpression | group | BEFREE | In conclusion, reduced degradation of filtered albumin in the proximal tubule is a common feature of glomerular diseases. | 29124787 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. | 29433915 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | It is remarkable that experimental models such as Heymann nephritis and cationic bovine serum albumin-induced MN in the rabbit predicted the pathomechanisms of the human glomerulopathy. | 28597189 | 2017 | ||||
|
0.080 | Biomarker | group | BEFREE | Fracture risk increases with age and lower serum albumin and is reduced if the primary renal diagnosis is glomerular disease. | 27257273 | 2017 | ||||
|
0.080 | Biomarker | group | BEFREE | Although the molecular basis for a potential causative role for albuminuria in progressive chronic kidney disease remains poorly understood, there have been several recent advances in our understanding of the role of albumin, and its molecular modifications, in the development and progression of glomerular disease. | 28735420 | 2017 | ||||
|
0.080 | Biomarker | group | BEFREE | The recent unraveling of the relationship between proteinuria and hypertriglyceridemia mediated by free fatty acids, albumin, and the secreted glycoprotein angiopoietin-like 4 (Angptl4) offers a unique opportunity to develop novel therapeutics for glomerular diseases. | 25005737 | 2015 | ||||
|
0.080 | Biomarker | group | BEFREE | Enhanced filtered load of proteins in glomerular diseases (overload proteinuria) results in significant increase in the rate of proximal tubular uptake that is true for all proteins tested so far, including albumin. | 8887257 | 1996 |