Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 AlteredExpression disease BEFREE COX-2 gene expression and methylation profile in Sapajus apella as an experimental model for gastric adenocarcinoma. 29767663 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 AlteredExpression disease BEFREE The immunohistochemistry was used to study the expression of COX-2 on 93 patients with gastric adenocarcinoma. 27314294 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 Biomarker disease BEFREE As a consequence, the expression of COX-2 and PCNA was found in cancer tissues with a higher strong reactivity rate, compared with the ANCTs (80.0 vs. 53.3%, P=0.011; 68.9 vs. 48.9%, P=0.047), and COX-2 was positively associated with lymph node metastasis of GAC patients (P=0.011). 24992958 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 AlteredExpression disease BEFREE We conclude that Hp promotes apoptosis in adenocarcinoma gastric epithelial cells in vitro and this is associated with activation of COX-2 and inhibition of HSP70. 22610150 2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 GeneticVariation disease BEFREE -765G > C COX-2 polymorphism with or without H pylori could be a marker for genetic susceptibility to gastric adenocarcinoma. 18330937 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 GeneticVariation disease BEFREE -765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia. 17006983 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 Biomarker disease BEFREE COX-2 may contribute to progression of tumor in human gastric adenocarcinoma. 12532441 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 AlteredExpression disease BEFREE Cox-2 is expressed by the neoplastic cells in the intestinal-type gastric adenocarcinoma and by precarcinogenic (dysplastic) lesions leading to this disease. 11448905 2001
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.090 Biomarker disease BEFREE These results provide clinical evidence that COX-2 may contribute to tumor progression in human gastric adenocarcinoma. 11223821 2001