Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.080 | AlteredExpression | disease | BEFREE | Together, PDE6D was found to be overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation. | 30901922 | 2019 | ||||
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0.080 | Biomarker | disease | BEFREE | The results also showed that psilostachyin-A could block the ERK/MAPK pathway, indicative of the cytotoxic effects of psilostachyin-A on liver cancer. | 31492830 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Taken together, our results emphasize the importance of the MEK/ERK pathway in liver cancer cell growth in vitro and in vivo and argue for a crucial role of ERK2 in this regulation. | 18521085 | 2008 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The protein levels of p-ERK, p-JNK and p-p38 and the protein levels of MMP-2 and MMP-9 were evaluated with western blot 48 h after siRNA-B-targeting BMP-2 was transfected into liver cancer SMMC7721 cells. | 20885449 | 2011 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Moreover, SATB1 expression and anoikis resistance were mainly regulated by HBV-encoded viral protein HBx through the activation of ERK and p38 MAPK signaling pathways to promote metastasis of liver cancer. | 31147803 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Current data showed that there were AMPK-ERK/CARM1 autophagic signaling pathways during the formation of liver cancer. | 31799198 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | From a clinical point of view, the ERK MAPK pathway and the PI3K/AKT pathway are activated in the majority of liver cancer. | 31312391 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | These results show that in addition to changes in the signaling pathways, such as the Ras-Raf-MEK-ERK pathway, altered mitochondrial DNA replication and protein folding in liver cancer are also worth studying further. | 23589362 | 2013 |