Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 GeneticVariation group BEFREE SERPINA1 deficiency is the most common genetic cause of hepatic disease in children and is frequently responsible for chronic liver disease in adults. 23584152 2013
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 Biomarker group BEFREE The AAT gene is mapped on chromosome 14 and has been associated with chronic liver disease and chronic obstructive pulmonary disease (COPD). 21727732 2011
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 GeneticVariation group BEFREE Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study. 20170533 2010
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 GeneticVariation group BEFREE We attempted to determine the role of alpha-1-antitrypsin (AAT) deficient variants as an etiologic factor for chronic liver disease in North Indian children. 20453271 2010
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 Biomarker group BEFREE alpha(1)-Antitrypsin (AT) deficiency is a hereditary disorder that may lead to early-onset emphysema, and chronic liver disease later in life. 20436173 2010
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 GeneticVariation group BEFREE The frequency of A1AT Z and other alleles was increased in children with chronic liver disease (n = 241) when compared with the published reference database (P < 0.001). 17204961 2007
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 Biomarker group BEFREE There are strong arguments to consider heterozygous AIAT deficiency as an important co-factor in the aetiology of chronic liver disease. 17519511 2007
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 Biomarker group BEFREE The present study was made to further the relationship between alpha-1-antitrypsin and the pathogenesis of chronic liver disease in dogs. 8762579 1996
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 Biomarker group BEFREE alpha 1-antitrypsin does not seem to play a role in the pathogenesis of chronic liver disease and hepatitis C virus infection in patients with porphyria cutanea tarda. 8781910 1996
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 GeneticVariation group BEFREE Polymerase chain reaction for detection of the alpha-1-antitrypsin Z allele in chronic liver disease. 2332597 1990
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.100 Biomarker group BEFREE Alpha-1-antitrypsin MZ phenotype and cryptogenic chronic liver disease in adults. 6354808 1983