Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.520 | Biomarker | disease | CTD_human | Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development. | 30556042 | 2018 | ||||
|
0.520 | Biomarker | disease | CTD_human | Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling. | 29142166 | 2017 | ||||
|
0.520 | Biomarker | disease | BEFREE | Our data show that the activation of a repressor of Gank, farnesoid X receptor, FXR, after initiation of liver cancer by Diethylnitrosamine (DEN) prevents the development of liver cancer by inhibiting Gank and rescuing tumor suppressor proteins. | 28535186 | 2017 | ||||
|
0.520 | AlteredExpression | disease | BEFREE | MiR-22-silenced cyclin A expression in colon and liver cancer cells is regulated by bile acid receptor. | 25596928 | 2015 | ||||
|
0.520 | Biomarker | disease | CTD_human | Suppression of autophagic flux by bile acids in hepatocytes. | 24189133 | 2014 | ||||
|
0.520 | Biomarker | disease | CTD_human | Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver. | 23178280 | 2013 | ||||
|
0.520 | Biomarker | disease | CTD_human | Mechanisms of STAT3 activation in the liver of FXR knockout mice. | 24091600 | 2013 | ||||
|
0.520 | Biomarker | disease | MGD | Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor. | 17283114 | 2007 | ||||
|
0.520 | Biomarker | disease | MGD | Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. | 17183066 | 2007 | ||||
|
0.520 | Biomarker | disease | MGD | Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. | 11030617 | 2000 |