Gene: CDH1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 GeneticVariation disease BEFREE Using Exome Aggregation Consortium control data, we confirm significant associations of heterozygous germ line mutations with BC for ATM (OR: 3.63, 95%CI: 2.67-4.94), CDH1 (OR: 17.04, 95%CI: 3.54-82), CHEK2 (OR: 2.93, 95%CI: 2.29-3.75), PALB2 (OR: 9.53, 95%CI: 6.25-14.51), and TP53 (OR: 7.30, 95%CI: 1.22-43.68). 29522266 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Germline CDH1 mutations in bilateral lobular carcinoma in situ. 24366306 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. 24733792 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study. 23709761 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC. 22850631 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells. 23053649 2012
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer. 21271559 2011
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Germline E-cadherin mutations in familial lobular breast cancer. 17660459 2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. 17097565 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. 10074450 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast. 7961105 1994
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.310 Biomarker disease CLINGEN E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. 2007622 1991