Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7704
Gene Symbol: ZBTB16
ZBTB16 		0.010 Biomarker disease BEFREE The downstream effectors, FOXO3a, PLZF and VEGF, are reported to be involved in angiogenesis, lymph node metastasis and poor survival in PC. 31087222 2020
Entrez Id: 3691
Gene Symbol: ITGB4
ITGB4 		0.010 AlteredExpression disease BEFREE ITGB4 and p-ITGB4-Y1510 were highly expressed in pancreatic cancer (n = 176) compared with normal pancreatic tissue (n = 171). 31242404 2020
Entrez Id: 5310
Gene Symbol: PKD1
PKD1 		0.010 AlteredExpression disease BEFREE PKD1 expression in PanCa was investigated by using immunohistochemistry. 31819177 2020
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B 		0.010 Biomarker disease BEFREE Our study demonstrates the critical role of TYRO3 in PC progression through Akt and ERK activation and suggests TYRO3 as a novel promising target for therapeutic strategies against PC. 31765735 2020
Entrez Id: 7041
Gene Symbol: TGFB1I1
TGFB1I1 		0.010 AlteredExpression disease BEFREE Statistical analysis revealed that Hic-5 expression was higher among the pancreatic cancer group than among the normal group and was negatively correlated with postoperative survival time among patients with pancreatic cancer. 31683179 2020
Entrez Id: 100885775
Gene Symbol: BANCR
BANCR 		0.010 Biomarker disease BEFREE LncRNA BANCR Promotes Pancreatic Cancer Tumorigenesis via Modulating MiR-195-5p/Wnt/β-Catenin Signaling Pathway. 31769353 2020
Entrez Id: 22868
Gene Symbol: FASTKD2
FASTKD2 		0.010 Biomarker disease BEFREE FASTKD2 might be a potential target for pancreatic cancer therapy. 31692063 2020
Entrez Id: 1113
Gene Symbol: CHGA
CHGA 		0.010 AlteredExpression disease BEFREE High CgA levels may predict poor prognosis in patients with pancreatic cancer, especially during metastatic stages. 31091213 2020
Entrez Id: 693192
Gene Symbol: MIR607
MIR607 		0.010 Biomarker disease BEFREE Besides, LINC01559 was revealed to be mainly in the cytoplasm of PC cells and therefore served as a ceRNA of Yes-associated protein (YAP) in PC cells via sponging miR-607. 31608998 2020
Entrez Id: 407020
Gene Symbol: MIR28
MIR28 		0.010 AlteredExpression disease BEFREE What is more, SEMA7A was found to be a target gene for miR-28-5p and was upregulated in PC. 31732974 2020
Entrez Id: 58516
Gene Symbol: SINHCAF
SINHCAF 		0.010 AlteredExpression disease BEFREE FAM60A has been found showing high levels in some cancer cells, including lung cancer (A549), and pancreatic cancer (Capan-2) cell lines. 31727367 2020
Entrez Id: 574442
Gene Symbol: MIR489
MIR489 		0.010 AlteredExpression disease BEFREE Compared with normal adjacent tissues and normal pancreatic cells, the expression of miR-489 was markedly down-regulated in PC tissues and cells. 31646811 2020
Entrez Id: 550643
Gene Symbol: NBDY
NBDY 		0.010 Biomarker disease BEFREE Importantly, KRAS was proved to mediate LINC01420-facilitated PC cell proliferation. 31562613 2020
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1 		0.010 Biomarker disease BEFREE Neoadjuvant chemotherapy/neoadjuvant chemoradiotherapy (NAC/NACRT) can be performed in patients with pancreatic cancer to improve survival. 31060118 2020
Entrez Id: 2746
Gene Symbol: GLUD1
GLUD1 		0.010 AlteredExpression disease BEFREE Clinically, XLOC_006390 was positively correlated with the mRNA level of GDH1, and c-Myc positively regulated GDH1 gene expression, which was tightly associated with PC patient prognosis. 31734356 2020
Entrez Id: 404550
Gene Symbol: C16orf74
C16orf74 		0.010 Biomarker disease BEFREE Thus, this study demonstrates that dimerized C16orf74, present in the cell membrane, is involved in pancreatic cancer invasion and proliferation. 31597713 2020
Entrez Id: 25907
Gene Symbol: TMEM158
TMEM158 		0.010 AlteredExpression disease BEFREE Collectively, TMEM158 was upregulated in PC and promoted PC cell proliferation, migration, and invasion through the activation of TGFβ1 and PI3K/AKT signaling pathways, highlighting its potential as a tumor promoter and a therapeutic target for PC. 31531884 2020
Entrez Id: 5313
Gene Symbol: PKLR
PKLR 		0.010 AlteredExpression disease BEFREE Furthermore, HK1, PKLR, and LDHA expression correlated positively with PC progression. 31689601 2020
Entrez Id: 7832
Gene Symbol: BTG2
BTG2 		0.010 AlteredExpression disease BEFREE Our results revealed that miR-27a was highly expressed, while BTG2 was poorly expressed in both PC tissues and cell lines. miR-27a targeted BTG2. 31724333 2020
Entrez Id: 5927
Gene Symbol: KDM5A
KDM5A 		0.010 Biomarker disease BEFREE A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism. 31641207 2020
Entrez Id: 100287616
Gene Symbol: LOXL1-AS1
LOXL1-AS1 		0.010 Biomarker disease BEFREE Therefore, the function of LOXL1-AS1 was further explored in PC, presenting that LOXL1-AS1 suppression inhibited cell proliferation and migration. 31732974 2020
Entrez Id: 64754
Gene Symbol: SMYD3
SMYD3 		0.010 Biomarker disease BEFREE To explore the role of SMYD3 in the pancreatic cancer. 31441002 2020
Entrez Id: 7504
Gene Symbol: XK
XK 		0.010 Biomarker disease BEFREE Neoadjuvant chemotherapy/neoadjuvant chemoradiotherapy (NAC/NACRT) can be performed in patients with pancreatic cancer to improve survival. 31060118 2020
Entrez Id: 259266
Gene Symbol: ASPM
ASPM 		0.010 Biomarker disease BEFREE Elucidating the roles of ASPM isoforms reveals a novel prognostic marker for pancreatic cancer. 31595972 2020
Entrez Id: 10892
Gene Symbol: MALT1
MALT1 		0.010 Biomarker disease BEFREE Therefore, we studied the impact of pharmacological MALT1 inhibition in pancreatic cancer and showed promising effects on tumor progression. 31291468 2020