Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR 		1.000 GeneticVariation disease UNIPROT
Entrez Id: 367
Gene Symbol: AR
AR 		1.000 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.800 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 8405
Gene Symbol: SPOP
SPOP 		0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.700 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 4601
Gene Symbol: MXI1
MXI1 		0.660 Biomarker disease CTD_human
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		0.500 Biomarker disease CTD_human
Entrez Id: 8379
Gene Symbol: MAD1L1
MAD1L1 		0.400 Biomarker disease CTD_human
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5 		0.390 Biomarker disease CTD_human Prostate cancer patients with CYP3A5*3/*3 and KLK -252A > G GG/AG genotypes had decreased OR of 0.70 with 95% CI 0.50-0.98 for high prostate-specific antigen levels at diagnosis. 18306354 2008
Entrez Id: 6541
Gene Symbol: SLC7A1
SLC7A1 		0.330 Biomarker disease CTD_human CaT1 expression correlates with tumor grade in prostate cancer. 11401523 2001
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.400 Biomarker disease CTD_human Endothelial nitric oxide synthase gene polymorphisms and the shedding of circulating tumour cells in the blood of prostate cancer patients. 12445681 2003
Entrez Id: 9
Gene Symbol: NAT1
NAT1 		0.360 Biomarker disease CTD_human NAT1 and NAT2 are both subject to genetic polymorphism in humans, and molecular epidemiological investigations suggest that NAT1 and/or NAT2 acetylator genotype modifies risk for prostate cancers. 12618593 2003
Entrez Id: 3489
Gene Symbol: IGFBP6
IGFBP6 		0.310 Therapeutic disease CTD_human IGFBP-6 therefore might be involved in the direct effects of DES in androgen-independent prostate cancer. 15846301 2005
Entrez Id: 8000
Gene Symbol: PSCA
PSCA 		0.400 Biomarker disease CTD_human PSCA in situ hybridization (ISH) was performed on the cancerous pretreatment biopsy or transurethral resection of prostate (TURP) tissue of 42 men with primarily organ-confined prostate cancer before CAA, and on their tumor tissue from radical retropubic prostatectomy after CAA with bicalutamide and goserelin acetate for 3 months prior to undergoing radical prostatectomy. 16015594 2005
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.320 Biomarker disease CTD_human Interleukin-1 receptor antagonist haplotype associated with prostate cancer risk. 16106254 2005
Entrez Id: 9687
Gene Symbol: GREB1
GREB1 		0.350 Biomarker disease CTD_human GREB1 is expressed in proliferating prostatic tissue and prostate cancer, is regulated by androgens, and suppression of GREB1 blocks androgen-induced growth suggesting GREB1 may be critically involved in prostate cancer proliferation. 16496412 2006
Entrez Id: 606293
Gene Symbol: KLKP1
KLKP1 		0.320 Biomarker disease CTD_human KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells. 16541416 2006
Entrez Id: 567
Gene Symbol: B2M
B2M 		0.330 Biomarker disease CTD_human Beta-2-microglobulin is an androgen-regulated secreted protein elevated in serum of patients with advanced prostate cancer. 17404077 2007
Entrez Id: 3925
Gene Symbol: STMN1
STMN1 		0.360 Biomarker disease CTD_human Stathmin expression and phosphorylation patterns were analyzed in mouse and human PCa cell lines as well as in human PCa tissue arrays. 17455228 2007
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		0.400 Biomarker disease CTD_human GSTM1 (0/0) gene polymorphism may be linked to prostate cancer risk and early age of onset in Chinese. 18304461 2008
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.400 Biomarker disease CTD_human Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 19011039 2009
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.400 Therapeutic disease CTD_human Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 19011039 2009
Entrez Id: 101669767
Gene Symbol: SCHLAP1
SCHLAP1 		0.380 Biomarker disease CTD_human SChLAP1 levels independently predict poor outcomes, including metastasis and prostate cancer-specific mortality. 24076601 2013
Entrez Id: 10551
Gene Symbol: AGR2
AGR2 		0.400 Biomarker disease CTD_human AGR2 SV-G and SV-H are potential diagnostic biomarkers for the non-invasive detection of PCa using urine exosomes. 25237833 2014
Entrez Id: 2078
Gene Symbol: ERG
ERG 		0.400 Biomarker disease CTD_human TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer. 28783165 2017