Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human C-Fos expression as a molecular marker in corticotropin-releasing factor-induced seizures. 8923670 1996
Entrez Id: 4803
Gene Symbol: NGF
NGF 		0.300 Biomarker phenotype CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Therapeutic phenotype CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997
Entrez Id: 3630
Gene Symbol: INS
INS 		0.300 Biomarker phenotype CTD_human Drug-induced convulsions. Report from Boston Collaborative Drug Surveillance Program. 4115818 1972
Entrez Id: 2593
Gene Symbol: GAMT
GAMT 		0.300 Biomarker phenotype CTD_human Guanidinoacetate methyltransferase deficiency identified in adults and a child with mental retardation. 15651030 2005
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Biomarker phenotype CTD_human Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism. 12646302 2003
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human Oxytocin infusion: acute hyponatraemia, seizures and coma. 19397503 2009
Entrez Id: 2572
Gene Symbol: GAD2
GAD2 		0.300 Biomarker phenotype CTD_human Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures. 8985701 1996
Entrez Id: 885
Gene Symbol: CCK
CCK 		0.300 Therapeutic phenotype CTD_human Anticonvulsant effects of caerulein, cholecystokinin octapeptide (CCK-8) and diazepam against seizures produced in mice by harman, thiosemicarbazide and isoniazid. 6265841 1981
Entrez Id: 11284
Gene Symbol: PNKP
PNKP 		0.300 Biomarker phenotype CTD_human Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. 20118933 2010
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1 		0.300 Biomarker phenotype CTD_human [The role of the opiate mechanisms of the hippocampus and substantia nigra in the behavioral and convulsive disorders in picrotoxin-induced kindling]. 1675896 1991
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5 		0.300 Biomarker phenotype CTD_human Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures. 14996991 2004
Entrez Id: 6792
Gene Symbol: CDKL5
CDKL5 		0.300 Biomarker phenotype CTD_human Historic, clinical, and prognostic features of epileptic encephalopathies caused by CDKL5 mutations. 22264704 2012
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human Syntocinon induced convulsion. 5493616 1970
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		0.300 Biomarker phenotype CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139 2016
Entrez Id: 4504
Gene Symbol: MT3
MT3 		0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker phenotype CTD_human Induced microseizures in West syndrome. 1656808 1991
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2 		0.300 Biomarker phenotype CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 4804
Gene Symbol: NGFR
NGFR 		0.300 Biomarker phenotype CTD_human p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. 10436046 1999
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1 		0.300 Biomarker phenotype CTD_human The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. 12091480 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Effects of dopamine D3 receptor agonists on pilocarpine-induced limbic seizures in the rat. 7936204 1994
Entrez Id: 6505
Gene Symbol: SLC1A1
SLC1A1 		0.300 Biomarker phenotype CTD_human Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes. 23262392 2013
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Therapeutic phenotype CTD_human Cardiac hypertrophy associated with ACTH therapy for childhood seizure disorder. 2821097 1987
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11 		0.300 Biomarker phenotype CTD_human The pattern of ATP-sensitive K+ channel subunits, Kir6.2 and SUR1 mRNA expressions in DG region is different from those in CA1-3 regions of chronic epilepsy induced by picrotoxin in rats. 18021373 2007
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker phenotype CTD_human Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. 21062901 2011