Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26503
Gene Symbol: SLC17A5
SLC17A5
0.010 Biomarker phenotype BEFREE Children's performance on the AST was meaningfully related to hyperactivity-inattention, externalizing behavior and overall level of childhood psychopathology. 31535948 2020
Entrez Id: 9211
Gene Symbol: LGI1
LGI1
0.010 GeneticVariation phenotype BEFREE The impact of difficulties on home life, friendships, school or work and/or leisure activities was greater in the EPT group (RR 4.28, 95% CI 2.89-6.35, p < 0.001), and hyperactivity/inattention and peer problems accounted for the largest differences. 30191335 2019
Entrez Id: 56925
Gene Symbol: LXN
LXN
0.010 Biomarker phenotype BEFREE The ECI-4 HI and IA subscales showed acceptable accuracy in identifying ADHD in boys and girls (areas under the curve ranged from .67 to .85). 30958025 2019
Entrez Id: 414
Gene Symbol: ARSD
ARSD
0.010 Biomarker phenotype BEFREE Infant RF was negatively associated with later traits of ASD (B = - 0.5, p = 0.01) and ADHD inattention (B = - 0.24, p = 0.02) but not hyperactivity (B = - 0.25, p = 0.10) or CU traits (B = 0.02, p = 0.86). 31351456 2019
Entrez Id: 4929
Gene Symbol: NR4A2
NR4A2
0.010 Biomarker phenotype BEFREE However, the association between NURR1 defects and the attention-deficit hyperactivity disorder (ADHD), a DA-associated brain disease characterized by hyperactivity, impulsivity and inattention, has never been demonstrated. 31455763 2019
Entrez Id: 6314
Gene Symbol: ATXN7
ATXN7
0.010 Biomarker phenotype BEFREE The Atxn7 OE mice displayed hyperactivity and impulsivity, but not inattention. 30125623 2019
Entrez Id: 9034
Gene Symbol: CCRL2
CCRL2
0.010 GeneticVariation phenotype BEFREE The domain of inattention and omission errors was related to occupational/vocational therapy engagement as well as a higher risk of present and future violence as measured by the HCR-20. 31133891 2019
Entrez Id: 27102
Gene Symbol: EIF2AK1
EIF2AK1
0.010 GeneticVariation phenotype BEFREE The domain of inattention and omission errors was related to occupational/vocational therapy engagement as well as a higher risk of present and future violence as measured by the HCR-20. 31133891 2019
Entrez Id: 23352
Gene Symbol: UBR4
UBR4
0.010 Biomarker phenotype BEFREE During attentive wakefulness, arithmetic violations elicited a succession of N400 and P600 effects, whereas no such activations could be recorded in sleep or in inattentive wakefulness. 30476318 2019
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
0.010 GeneticVariation phenotype BEFREE The domain of inattention and omission errors was related to occupational/vocational therapy engagement as well as a higher risk of present and future violence as measured by the HCR-20. 31133891 2019
Entrez Id: 7069
Gene Symbol: THRSP
THRSP
0.010 Biomarker phenotype BEFREE The THRSP OE mice exhibited inattention in the novel-object recognition and Y-maze test, but not hyperactivity in the open-field test and impulsivity in the cliff-avoidance and delay-discounting task. 30138648 2018
Entrez Id: 6611
Gene Symbol: SMS
SMS
0.010 Biomarker phenotype BEFREE There were strong correlations between FLV Hyperactivity and Cognitive problems/Inattention scores and ADHD-SRS scores of Impulsivity/Hyperactivity ( r = .90) and Inattention ( r = .68) and also strong correlations between FLV Opposition score and the CBCL scores of Aggressive behavior ( r = .84) and Rule-breaking behavior ( r = .66). 29562852 2018
Entrez Id: 2047
Gene Symbol: EPHB1
EPHB1
0.010 GeneticVariation phenotype BEFREE Six single nucleotide polymorphisms (rs28386840, rs2242446, rs3785143, rs3785157, rs5569, rs7194256 SNP) were studied across the NET gene in 163 ADHD children (age: 9.3±2.6; 86.5% male) using ADHD-RS hyperactivity-impulsivity and inattention scales. 29374517 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.010 Biomarker phenotype BEFREE A significant association between decreased hyperactivity/inattention and increased leptin was found (OR = 0.22, 95% CI: 0.06-0.89). 29324697 2018
Entrez Id: 344875
Gene Symbol: COL6A4P1
COL6A4P1
0.010 Biomarker phenotype BEFREE A logistic regression analysis model with the DIVA and measures of inattention, impulsivity, and activity from continuous performance tests (CPTs) showed a sensitivity of 90.0 and a specificity of 83.3. 26681530 2018
Entrez Id: 2004
Gene Symbol: ELK3
ELK3
0.010 GeneticVariation phenotype BEFREE Six single nucleotide polymorphisms (rs28386840, rs2242446, rs3785143, rs3785157, rs5569, rs7194256 SNP) were studied across the NET gene in 163 ADHD children (age: 9.3±2.6; 86.5% male) using ADHD-RS hyperactivity-impulsivity and inattention scales. 29374517 2018
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.010 GeneticVariation phenotype BEFREE SYT1-rs2251214 was associated with the categorical short-term response to IR-MPH (P=0.006, P<sub>FDR</sub>=0.028), and with the percentage of inattention and oppositional defiant disorder symptoms reduction (P=0.007, P<sub>FDR</sub>=0.028 and P=0.017, P<sub>FDR</sub>=0.048, respectively). 28461697 2018
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
0.010 Biomarker phenotype BEFREE In multivariable adjusted models using gamma regression, a 0.5 mg/L higher MUF<sub>cr</sub> (approximately one IQR higher) corresponded with significantly higher scores on the CRS-R for DSM-IV Inattention (2.84 points, 95% CI: 0.84, 4.84) and DSM-IV ADHD Total Index (2.38 points, 95% CI: 0.42, 4.34), as well as the following symptom scales: Cognitive Problems and Inattention (2.54 points, 95% CI: 0.44, 4.63) and ADHD Index (2.47 points; 95% CI: 0.43, 4.50). 30316181 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.010 AlteredExpression phenotype BEFREE The increase of serum BDNF levels with methylphenidate treatment after 8 weeks was significantly higher in the inattentive group (p = 0.005). 28710695 2018
Entrez Id: 140821
Gene Symbol: RSS
RSS
0.010 Biomarker phenotype BEFREE There were strong correlations between FLV Hyperactivity and Cognitive problems/Inattention scores and ADHD-SRS scores of Impulsivity/Hyperactivity ( r = .90) and Inattention ( r = .68) and also strong correlations between FLV Opposition score and the CBCL scores of Aggressive behavior ( r = .84) and Rule-breaking behavior ( r = .66). 29562852 2018
Entrez Id: 3376
Gene Symbol: IARS1
IARS1
0.010 GeneticVariation phenotype BEFREE Increased inattention symptoms were associated with IRS ≥ 9, short and long sleep duration in fully adjusted models (OR = 1.10, 95% CI 1.06-1.14; RRR = 1.06, 95% CI 1.02-1.09; RRR = 1.16, 95% CI 1.05-1.28, respectively). 29458702 2018
Entrez Id: 115004
Gene Symbol: CGAS
CGAS
0.010 Biomarker phenotype BEFREE Within patients carrying at least one DAT 9 allele (DAT 9/x), methylation at positions CpG2 and/or CpG6 correlated with recovery, as evident from delta-CGAS scores as well as delta Conners' scales ('inattentive' and 'hyperactive' subscales). 28822049 2018
Entrez Id: 10017
Gene Symbol: BCL2L10
BCL2L10
0.010 Biomarker phenotype BEFREE A logistic regression analysis model with the DIVA and measures of inattention, impulsivity, and activity from continuous performance tests (CPTs) showed a sensitivity of 90.0 and a specificity of 83.3. 26681530 2018
Entrez Id: 89832
Gene Symbol: CHRFAM7A
CHRFAM7A
0.010 AlteredExpression phenotype BEFREE On exploration of the factor structure of psychopathology using principal component analysis, all the negative symptoms-affective flattening, alogia, apathy, anhedonia and inattention were found to be inversely associated with CHRFAM7A expression. 29305655 2018
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.010 GeneticVariation phenotype BEFREE The GRIN2B rs2284411 C/C genotype showed significantly better treatment response as assessed by ADHD-RS inattention ( p=0.009) and CGI-I scores ( p=0.009), and there was a nominally significant association in regard to ADHD-RS hyperactivity-impulsivity ( p=0.028) and total ( p=0.023) scores, after adjusting for age, sex, IQ, baseline Clinical Global Impression-Severity (CGI-S) score, baseline ADHD-RS total score, and final MPH dose. 27624150 2017