Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.330 Biomarker disease CTD_human
Entrez Id: 351
Gene Symbol: APP
APP 		0.400 Biomarker disease CTD_human Vitamin E protects nerve cells from amyloid beta protein toxicity. 1497677 1992
Entrez Id: 351
Gene Symbol: APP
APP 		0.400 Biomarker disease CTD_human Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. 1671712 1991
Entrez Id: 351
Gene Symbol: APP
APP 		0.400 Biomarker disease CTD_human Mis-sense mutation Val----Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease. 1678058 1991
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Therapeutic disease CTD_human Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease. 7477348 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE An increased frequency of apolipoprotein E E4 allele has been reported in patients with late onset Alzheimer's disease. 7477910 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 Biomarker disease BEFREE We suggest this hypothesis is compatible with the current literature regarding APOE and AD. 7485228 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE The apolipoprotein E (apoE) gene locus has recently been associated with late-onset Alzheimer's disease. 7534068 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE The epsilon 4 allele of apolipoprotein E has been associated with an increased risk of late-onset Alzheimer's disease. 7566000 1995
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		0.300 Biomarker disease CTD_human The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease. 7574463 1995
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.400 Biomarker disease CTD_human Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. 7596406 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Apo E genotypes in multiple sclerosis, Parkinson's disease, schwannomas and late-onset Alzheimer's disease. 7700274 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians. 7746404 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE A random sample of 60 late-onset Alzheimer's disease (AD) cases from a population-based study were apolipoprotein E (apoE) genotyped and clinically examined with a 3-year interval. 7746480 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease. 7755354 1995
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE It was suggested that in contrast to the E4 allele, the E2 allele of the apolipoprotein E gene (APOE*2) has a protective effect for late-onset Alzheimer's disease and early-onset Alzheimer's disease (EOAD). 7755355 1995
Entrez Id: 4129
Gene Symbol: MAOB
MAOB 		0.300 Biomarker disease CTD_human Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. 7816197 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. 7920638 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE An association between sporadic and familial late-onset Alzheimer's disease and polymorphisms of apolipoprotein E located on chromosome 19 suggests a new genetic model of this condition. 7952237 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus. 7970184 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE A significant association was observed between late-onset Alzheimer's disease and the epsilon 4 (112Cys-->Arg) allele of apolipoprotein E; however, no association was detected with apolipoprotein CII. 8024269 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE We assessed whether the APOE genotype had an influence on the age of onset of AD in chromosome 14 linked early-onset AD families. 8047278 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Several studies have reported an association of the apolipoprotein E allele epsilon 4 (APOE*4) to familial and sporadic late-onset Alzheimer's disease (LOAD). 8075646 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 GeneticVariation disease BEFREE Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. 8103823 1993
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.400 Biomarker disease BEFREE The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease. 8128960 1994