×
Entrez Id:
5328
Gene Symbol:
PLAU
PLAU
0.330
Biomarker
disease
CTD_human
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.400
Biomarker
disease
CTD_human
Vitamin E protects nerve cells from amyloid beta protein toxicity.
1497677
1992
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.400
Biomarker
disease
CTD_human
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.
1671712
1991
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.400
Biomarker
disease
CTD_human
Mis-sense mutation Val----Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease.
1678058
1991
×
Entrez Id:
1392
Gene Symbol:
CRH
CRH
0.300
Therapeutic
disease
CTD_human
Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease.
7477348
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
An increased frequency of apolipoprotein E E4 allele has been reported in patients with late onset Alzheimer's disease .
7477910
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
Biomarker
disease
BEFREE
We suggest this hypothesis is compatible with the current literature regarding APOE and AD .
7485228
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
The apolipoprotein E (apoE ) gene locus has recently been associated with late-onset Alzheimer's disease .
7534068
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
The epsilon 4 allele of apolipoprotein E has been associated with an increased risk of late-onset Alzheimer's disease .
7566000
1995
×
Entrez Id:
1565
Gene Symbol:
CYP2D6
CYP2D6
0.300
Biomarker
disease
CTD_human
The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease.
7574463
1995
×
Entrez Id:
5663
Gene Symbol:
PSEN1
PSEN1
0.400
Biomarker
disease
CTD_human
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
7596406
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Apo E genotypes in multiple sclerosis, Parkinson's disease, schwannomas and late-onset Alzheimer's disease .
7700274
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians.
7746404
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
A random sample of 60 late-onset Alzheimer's disease (AD ) cases from a population-based study were apolipoprotein E (apoE ) genotyped and clinically examined with a 3-year interval.
7746480
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease .
7755354
1995
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
It was suggested that in contrast to the E4 allele, the E2 allele of the apolipoprotein E gene (APOE *2) has a protective effect for late-onset Alzheimer's disease and early-onset Alzheimer's disease (EOAD).
7755355
1995
×
Entrez Id:
4129
Gene Symbol:
MAOB
MAOB
0.300
Biomarker
disease
CTD_human
Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography.
7816197
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease .
7920638
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
An association between sporadic and familial late-onset Alzheimer's disease and polymorphisms of apolipoprotein E located on chromosome 19 suggests a new genetic model of this condition.
7952237
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus.
7970184
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
A significant association was observed between late-onset Alzheimer's disease and the epsilon 4 (112Cys-->Arg) allele of apolipoprotein E ; however, no association was detected with apolipoprotein CII.
8024269
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
We assessed whether the APOE genotype had an influence on the age of onset of AD in chromosome 14 linked early-onset AD families.
8047278
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Several studies have reported an association of the apolipoprotein E allele epsilon 4 (APOE*4 ) to familial and sporadic late-onset Alzheimer's disease (LOAD ).
8075646
1994
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
GeneticVariation
disease
BEFREE
Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.
8103823
1993
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.400
Biomarker
disease
BEFREE
The apolipoprotein E /CI/CII gene cluster and late-onset Alzheimer disease .
8128960
1994