Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3577
Gene Symbol: CXCR1
CXCR1
0.070 AlteredExpression disease BEFREE Low CXCR1 expression was also detected in children with acute pyelonephritis. 11404374 2001
Entrez Id: 11334
Gene Symbol: TUSC2
TUSC2
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 50807
Gene Symbol: ASAP1
ASAP1
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 55149
Gene Symbol: MTPAP
MTPAP
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 5068
Gene Symbol: REG3A
REG3A
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 8853
Gene Symbol: ASAP2
ASAP2
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 10914
Gene Symbol: PAPOLA
PAPOLA
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 11333
Gene Symbol: PDAP1
PDAP1
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 10884
Gene Symbol: MRPS30
MRPS30
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 55
Gene Symbol: ACP3
ACP3
0.010 GeneticVariation disease BEFREE In total, 103 E. coli strains isolated from patients with acute pyelonephritis (59 uncomplicated pyelonephritis (UAP) and 44 complicated pyelonephritis (CAP)) were characterized by RFLP of the intergenic spacer region 16S-23S rRNA, the presence of three alternative sequences found in the polymorphic V6 loop of the 16S rRNA gene, the presence of the pap gene, and antibiotic susceptibility. 11531978 2001
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.020 GeneticVariation disease BEFREE Since the ACE gene deletion polymorphism is a known risk factor for progressive glomerulosclerosis in chronic renal diseases, we have investigated the relationship between the ACE genotypes and the development of renal scarring after APN. 12172760 2002
Entrez Id: 80232
Gene Symbol: WDR26
WDR26
0.010 AlteredExpression disease BEFREE The aim of the present study was to investigate the effects of IL-1beta and Escherichia coli on the expression and secretion of MIP-2, the mouse equivalent to human IL-8, MCP-1 and RANTES in the kidneys of mice with acute pyelonephritis. 12562381 2003
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
0.010 Biomarker disease BEFREE The aim of the present study was to investigate the effects of IL-1beta and Escherichia coli on the expression and secretion of MIP-2, the mouse equivalent to human IL-8, MCP-1 and RANTES in the kidneys of mice with acute pyelonephritis. 12562381 2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.010 Biomarker disease BEFREE The aim of the present study was to investigate the effects of IL-1beta and Escherichia coli on the expression and secretion of MIP-2, the mouse equivalent to human IL-8, MCP-1 and RANTES in the kidneys of mice with acute pyelonephritis. 12562381 2003
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
0.010 AlteredExpression disease BEFREE The aim of the present study was to investigate the effects of IL-1beta and Escherichia coli on the expression and secretion of MIP-2, the mouse equivalent to human IL-8, MCP-1 and RANTES in the kidneys of mice with acute pyelonephritis. 12562381 2003
Entrez Id: 259
Gene Symbol: AMBP
AMBP
0.040 Biomarker disease BEFREE The studies suggest that distinct molecular defects can cause the clinical entity of acute pyelonephritis with renal scarring, and suggest that the susceptibility to UTI in certain patient groups may have a genetic basis. 12848471 2003
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.010 Biomarker disease BEFREE Urinary levels of tissue inhibitor of metalloproteinase 1 (TIMP-1) higher than those of matrix metalloproteinase 9 (MMP-9) during acute pyelonephritis have previously been associated with a higher degree of acute inflammation and of postinfective renal scarring. 14688084 2004
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
0.010 Biomarker disease BEFREE Urinary levels of tissue inhibitor of metalloproteinase 1 (TIMP-1) higher than those of matrix metalloproteinase 9 (MMP-9) during acute pyelonephritis have previously been associated with a higher degree of acute inflammation and of postinfective renal scarring. 14688084 2004
Entrez Id: 54658
Gene Symbol: UGT1A1
UGT1A1
0.010 GeneticVariation disease BEFREE UGT1A1 promoter polymorphism as a predisposing factor of hyperbilirubinaemia in neonates with acute pyelonephritis. 16798708 2006
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
0.010 GeneticVariation disease BEFREE Determination of MBL2 polymorphisms could be useful for assessing the risk of septic shock in women undergoing acute pyelonephritis. 17202308 2007
Entrez Id: 3577
Gene Symbol: CXCR1
CXCR1
0.070 GeneticVariation disease BEFREE Interleukin-8 and CXCR1 receptor functional polymorphisms and susceptibility to acute pyelonephritis. 17296422 2007
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.040 GeneticVariation disease BEFREE Interleukin-8 and CXCR1 receptor functional polymorphisms and susceptibility to acute pyelonephritis. 17296422 2007
Entrez Id: 3577
Gene Symbol: CXCR1
CXCR1
0.070 AlteredExpression disease BEFREE CXCR1 expression was investigated as a factor predisposing to APN, because low CXCR1 expression has been associated with disease susceptibility in mice and disease-prone children. 17357062 2007
Entrez Id: 3577
Gene Symbol: CXCR1
CXCR1
0.070 Biomarker disease BEFREE The IL-8 receptor, CXCR1, was identified as a candidate gene when mIL-8Rh mutant mice developed acute pyelonephritis (APN) with severe tissue damage. 17786197 2007
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.040 Biomarker disease BEFREE The IL-8 receptor, CXCR1, was identified as a candidate gene when mIL-8Rh mutant mice developed acute pyelonephritis (APN) with severe tissue damage. 17786197 2007