Of particular interest are the genes being related to MetS (binary) in this study, but not to any of the MetS components in past studies, such as <i>WDR48, KLF14, NAADL1, GADD45G,</i> and <i>OR5R1,</i> as well as the two loci that have been associated with all five MetS components in past studies, <i>SNX10</i> and <i>C5orf67.</i> A pathway analysis of the 93 independent loci showed the immune system, transportation of small molecules, and metabolism to be enriched.