| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | Furthermore, SBP decreased the severity of MS and its complications by adjusting the expression of several mitochondrial proteins, including UCP2, Cytochrome b and ATPase. | 29551973 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | In the current study we aimed to investigate the major components of metabolic syndrome in patients with non-alcoholic fatty liver disease (NAFLD) and nutritional intakes according to different genotype of uncoupling protein-2 (UCP2) -866G/A gene polymorphism in these patients. | 27301474 | 2016 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The purpose of this study was to assess whether genetic variation in UCP2 may affect exercise-mediated changes in adipocytokines and markers of metabolic syndrome in postmenopausal obese women. | 24659521 | 2014 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our findings indicate that the uncoupling protein 2 gene -866G/A polymorphism may increase the risks of central obesity and metabolic syndrome, with greater effects on Asian men. | 16741267 | 2006 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Thus, measures to increase UCP2 expression in vascular endothelial cells may aid in preventing the development and progression of atherosclerosis in patients with metabolic syndrome. | 15905464 | 2005 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The -866G/A variants of the UCP2 gene are not associated with either obesity or other features of the metabolic syndrome in the studied groups of the Italian population. | 14974928 | 2003 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | From these data, we conclude that the C-->T substitution in exon 4 of the UCP2 gene does not contribute to the predisposition to be affected by the Metabolic Syndrome. | 12385772 | 2002 | ||||
|
0.080 | Biomarker | disease | BEFREE | No association was found between the UCP2 gene and BMR in patients with MSDR or in healthy controls. | 9724080 | 1998 |