×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
High performance plasma amyloid-β biomarkers for Alzheimer's disease.
29420472
2018
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers.
30320580
2018
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease.
28448946
2017
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease.
27117003
2016
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis.
25352456
2015
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer's Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation.
25714973
2015
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms.
23827522
2013
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model.
22507317
2012
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
pH-Dependent Cu(II) coordination to amyloid-β peptide: impact of sequence alterations, including the H6R and D7N familial mutations.
21980910
2011
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Increasing the predictive accuracy of amyloid-β blood-borne biomarkers in Alzheimer's disease.
21157020
2011
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Early effects of aluminum chloride on beta-secretase mRNA expression in a neuronal model of beta-amyloid toxicity.
20111991
2010
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease.
21209907
2010
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices.
20157255
2010
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
On the metal ion (Zn(2+), Cu(2+)) coordination with beta-amyloid peptide: DFT computational study.
20640797
2010
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.
19286555
2009
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease.
19818510
2009
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin.
18583042
2008
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease.
16969627
2007
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
"How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the ""LEARn"" model (latent early-life associated regulation) may explain the triggering of AD."
17430250
2007
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions.
17239395
2007
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease.
16651627
2006
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease.
16492752
2006
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Abeta) of Alzheimer's disease.
16266835
2006
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease.
16325427
2006
×
Entrez Id:
351
Gene Symbol:
APP
APP
0.300
Biomarker
disease
CTD_human
Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.
15591071
2005