Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. 15993441 2005
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). 12192006 2002
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Vitamin E protects nerve cells from amyloid beta protein toxicity. 1497677 1992
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. 27117003 2016
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. 15590663 2005
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease. 19818510 2009
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human On the metal ion (Zn(2+), Cu(2+)) coordination with beta-amyloid peptide: DFT computational study. 20640797 2010
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer's Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation. 25714973 2015
Entrez Id: 351
Gene Symbol: APP
APP
0.300 Biomarker disease CTD_human Peroxisomal proliferation protects from beta-amyloid neurodegeneration. 16204253 2005