Gene: CTNNB1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE MicroRNA-1275 induces radiosensitization in oesophageal cancer by regulating epithelial-to-mesenchymal transition via Wnt/β-catenin pathway. 31733028 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE AT‑101 induces G1/G0 phase arrest via the β‑catenin/cyclin D1 signaling pathway in human esophageal cancer cells. 30483745 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE Epigenetic deregulations of Wnt/β-catenin and transforming growth factor beta-Smad pathways in esophageal cancer: Outcome of DNA methylation. 30880778 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE Pin1 is a critical therapeutic and preventive target in esophageal cancer because of its positive regulation of β-catenin and cyclin D1. 28325828 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 AlteredExpression disease BEFREE Our study elucidates a mechanism of NDRG1-regulated Wnt pathway activation and EMT via affecting TLE2 and  β-catenin expression in esophageal cancer cells. 27414086 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE These results suggested that PKCι positively regulated β-catenin through negatively regulated autophagy and depletion of PKCι promoted apoptosis via autophagic degradation of β-catenin in esophageal cancer cells. 23359356 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE Loss of LKB1 expression may result in the deregulation of WNT/β-catenin pathway to promote malignant progression of esophageal cancer. 24022664 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 AlteredExpression disease BEFREE The purpose of this study is to test whether inhibition of beta-catenin or overexpression of p53 can decrease survivin expression and render esophageal cancer cells more susceptible to apoptosis. 20236666 2010
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE LEF1 and CTNNB1 may be the important genes causing the esophageal cancer cell radioresistance. 20868558 2010
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 AlteredExpression disease BEFREE This study shows that beta-catenin accumulation and nuclear localisation is not indicative of transcriptional activity, and therefore is not supportive of a major role in these oesophageal cancer cells. 17631645 2007
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 AlteredExpression disease BEFREE Four (8%) esophageal cancer tissues showed high nuclear beta-catenin staining. 17309796 2007
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 GeneticVariation disease BEFREE beta-Catenin splice variants and downstream targets as markers for neoplastic progression of esophageal cancer. 16114033 2005
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 AlteredExpression disease BEFREE We hypothesized that down-regulation of beta catenin would inhibit the growth of human esophageal cancer. 14752418 2004
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 GeneticVariation disease BEFREE None of the 34 esophageal cancers examined carried mutations in beta-catenin exon 3. 12498294 2002
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.100 Biomarker disease BEFREE Cytoplasmic beta-catenin in esophageal cancers. 10096251 1999