In addition, the risk-score model -0.0053*log<sub>2</sub>(<i>CADM2</i>)+0.0168*log<sub>2</sub>(<i>SERPINE1</i>)-0.0073*log<sub>2</sub>(ADAMTS9-AS2)+0.0905*log<sub>2</sub>(PVT1)+0.0047*log<sub>2</sub>(hsa-miR372)-0.0193*log<sub>2</sub>(hsa-miR145), (log<sub>2</sub>[gene count]) could improve diagnosis of EC with an AUC of 0.988.
In this review, we illustrate the various functions of PVT1 during the different stages in the complex process of digestive system tumours (including oesophageal cancer, gastric cancer, colorectal cancer, hepatocellular carcinoma and pancreatic cancer).