| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | We showed that garcinol treatment dose-dependently suppressed TGF-β1-activated Smad and non-Smad pathway, inhibiting esophageal cancer cell metastasis. | 31371781 | 2020 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The combination of neutrophil count and TGF-β1 level was an independent prognostic factor for lung and esophageal cancers patients. | 30693787 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Transforming growth factor-beta1 promotes the migration and invasion of sphere-forming stem-like cell subpopulations in esophageal cancer. | 26096658 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Here we investigate the role of FBXL19-mediated Rac3 degradation in TGFβ1-induced E-cadherin down-regulation in esophageal cancer cells. | 24684802 | 2014 | ||||
|
0.080 | Biomarker | disease | BEFREE | Esophageal cancer, which frequently exhibits coordinated loss of E-cadherin (Ecad) and transforming growth factor beta (TGFbeta) receptor II (TbetaRII), has a high mortality rate. | 20563251 | 2010 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Expression of decorin in esophageal cancer in relation to the expression of three isoforms of transforming growth factor-beta (TGF-beta1, -beta2, and -beta3) and matrix metalloproteinase-2 activity. | 19212830 | 2009 | ||||
|
0.080 | Biomarker | disease | BEFREE | The epithelial-mesenchymal transition (EMT) induced by VHL/HIF-1alpha-TGF-beta1 pathway might be the underlying mechanism responsible to the more aggressive tumor growth in UCP-positive esophageal cancer. | 19083192 | 2009 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Northern blot analysis revealed 3-fold and 4-fold increases (p < 0.05) in TGF-beta1 and CTGF mRNA levels, respectively, in esophageal cancer in comparison with normal controls, whereas TbetaR-I mRNA levels were significantly decreased and TbetaR-II mRNA levels were unchanged in the cancer samples. | 11910473 | 2002 |