Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE <b>Background:</b> Long noncoding RNA MALAT1 has been previously reported in the carcinogenesis of several tumors, and its potential functional polymorphisms have also been investigated in various diseases. 31788131 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE MALAT1 was speculated to regulate tumorigenesis via HuR-TIA-1-mediated autophagic activation. 27371730 2016
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been reported to be upregulated and contributed to ovarian cancer tumorigenesis. 29548748 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA (lncRNA) that is involved in tumorigenesis. 31305205 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 AlteredExpression phenotype BEFREE Metastasis Associated Lung Adenocarcinoma Transcript 1: An update on expression pattern and functions in carcinogenesis. 31712117 2020
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE A MALAT1/HIF-2α feedback loop contributes to arsenite carcinogenesis. 26735578 2016
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Additionally, MALAT1 knockdown also suppressed the tumorigenesis of prostate cancer cells in nude mice. 30642743 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Besides, we would investigate the effect of MALAT1 on the proliferation of glioma stem cells and glioma tumorigenesis. 29808528 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 AlteredExpression phenotype BEFREE Collectively, the current findings suggest that upregulation of MALAT1 in OC may facilitate tumorigenesis and metastasis. 28587379 2017
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 AlteredExpression phenotype BEFREE Elevated expression of MALAT-1 in OSCC may play a role in tumorigenesis and/or metastasis. 31360193 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Here using a collection of breast cancer cells and in vitro and in vivo migration assays we characterized the dynamics of expression and demonstrated that TALAM1 regulates and synergizes with MALAT1 during tumorigenesis. 31382922 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE In addition, the effects of MALAT1 on RCC tumorigenesis were evaluated in vivo by nude mouse tumorigenesis. 31250518 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 GeneticVariation phenotype BEFREE In order to provide more details on the genetic events of MHL tumorigenesis, capture-based next generation sequencing (NGS) targeted to loci recently shown to be involved in a translocation in a case of UES arising in MHL (specifically, the MALAT1 gene on chromosome 11 and a gene poor region termed MHLB1 on chromosome 19) was performed on formalin fixed paraffin embedded tissue from seven cases of MHL. 24120702 2013
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE In summary, our present study identified the IL-8/STAT3/MALAT1 axis as key regulators during prostate tumorigenesis and therefore demonstrated a new mechanism for the MALAT1 transcriptional regulation. 30591689 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE In summary, we establish and characterize a non-canonical PTEN-microRNA-MALAT1 axis that regulates tumorigenesis and describe for the first time that the MALAT1 lncRNA possesses novel tumor suppressive properties in colon and breast cancers. 29574704 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE In this review, we first update on the role of MALAT1 in tumorigenesis and then discuss possible molecular mechanisms that underline the MALAT1-mediated gene regulation, leading to cancer invasion and metastasis. 27814602 2017
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Lastly, MALAT1 bound Ezh2 and oncogenesis facilitated by MALAT1 was inhibited by Ezh2 depletion, thereby blocking epithelial-mesenchymal transition via E-cadherin recovery and β-catenin downregulation. 25600645 2015
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE LncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has recently been identified to be involved in tumorigenesis of several cancers such as lung cancer, pancreatic cancer, and cervical cancer. 25480417 2015
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE LncRNA metastasis-associated lung adenocarcinoma transcript 1(MALAT1) has recently been identified to be involved in tumorigenesis of several cancers such as lung cancer, bladder cancer and so on. 26461224 2015
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 AlteredExpression phenotype BEFREE LncRNA MALAT1 is expressed in various tissues and plays a critical role in cell proliferation, including tumorigenesis and metastasis. 30026840 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE LncRNA MALAT1 promotes tumorigenesis and immune escape of diffuse large B cell lymphoma by sponging miR-195. 30898647 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Long non-coding RNA Malat1 has been widely identified as an oncogene which shows a significant relationship with tumorigenesis in colorectal cancer (CRC). 31372165 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 AlteredExpression phenotype BEFREE miR-425-5p decreases LncRNA MALAT1 and TUG1 expressions and suppresses tumorigenesis in osteosarcoma via Wnt/β-catenin signaling pathway. 30986552 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Mounting evidence shows that the long non-coding RNA MALAT1 plays a pivotal role in tumorigenesis and metastasis, but the functional significance of MALAT1 in bladder transitional cell carcinoma (BTCC) remains unclear. 29736319 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
0.100 Biomarker phenotype BEFREE Multiple studies have suggested an oncogenic role of MALAT1 and high-mobility group protein B1 (HMGB1) in OS tumorigenesis and metastasis, but the effects and mechanisms are not unanimous. 28346809 2017