Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.160 | GeneticVariation | disease | GWASCAT | Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. | 29892016 | 2018 | ||||
|
0.160 | Biomarker | disease | BEFREE | Antimony enhances c-Myc stability in prostate cancer via activating CtBP2-ROCK1 signaling pathway. | 30098506 | 2018 | ||||
|
0.160 | Biomarker | disease | BEFREE | These results highlight the association between CtBP2 and angiogenesis in PCa and indicate that CtBP2 may be a potential therapeutic target for PCa. | 28677795 | 2017 | ||||
|
0.160 | Biomarker | disease | BEFREE | Taken together, our investigations demonstrated that low-expression of CtBP2 could highly inhibit proliferation of prostate cancer by c-Myc induced signaling, suggesting that targeting CtBP2 may yield a viable anti-tumor strategy by restraining tumor progression in prostate cancer. | 24835310 | 2014 | ||||
|
0.160 | Biomarker | disease | BEFREE | Expression patterns of candidate susceptibility genes HNF1β and CtBP2 in prostate cancer: association with tumor progression. | 24332637 | 2014 | ||||
|
0.160 | Biomarker | disease | BEFREE | Overall, our results show how CtBP2 contributes to prostate cancer progression by modulating AR and oncogenic signaling. | 25228652 | 2014 | ||||
|
0.160 | GeneticVariation | disease | BEFREE | After allowing for multiple testing, none of the SNPs examined were significantly associated with growth factor or hormone concentrations, and the SNP-prostate cancer associations did not differ by these concentrations, although 4 interactions were marginally significant (MSMB-rs10993994 with androstenedione (uncorrected P = 0.008); CTBP2-rs4962416 with IGFBP-3 (uncorrected P = 0.003); 11q13.2-rs12418451 with IGF-1 (uncorrected P = 0.006); and 11q13.2-rs10896449 with SHBG (uncorrected P = 0.005)). | 22459122 | 2012 | ||||
|
0.160 | GeneticVariation | disease | GWASCAT | Multiple loci identified in a genome-wide association study of prostate cancer. | 18264096 | 2008 |