Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.170 | Biomarker | disease | BEFREE | These results suggest that MYO6 plays an essential role in the progression of prostate cancer and silencing of MYO6 may be a promising therapeutic approach for prostate cancer. | 27431378 | 2016 | ||||
|
0.170 | Biomarker | disease | BEFREE | Myosin VI has been reported to be associated with the progression of ovarian and prostate cancer. | 26324058 | 2015 | ||||
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0.170 | Biomarker | disease | BEFREE | Thus, to understand the role of myosin VI in prostate cancer development, we have characterized its intracellular localization and function in the prostate cancer cell line LNCaP. | 19855435 | 2010 | ||||
|
0.170 | AlteredExpression | disease | BEFREE | This finding was matched to the upregulation of myosin VI in established prostate cancer cell lines. | 20353999 | 2010 | ||||
|
0.170 | AlteredExpression | disease | BEFREE | We confirmed previous results of myosin VI overexpression in human prostate cancer tissue, as in some cases malignant epithelium was more intensively stained than benign epithelium. | 19787211 | 2009 | ||||
|
0.170 | AlteredExpression | disease | BEFREE | 6q loss in nonrearranged prostate cancer is accompanied by gene expression deregulation in an independent dataset and by protein deregulation of MYO6. | 19156837 | 2009 | ||||
|
0.170 | AlteredExpression | disease | BEFREE | Depletion of myosin VI expression was also accompanied by global gene expression changes reflective of attenuated tumorigenic potential, as marked by a nearly 10-fold induction of TXNIP (VDUP1), a tumor suppressor with decreased expression in prostate cancer specimens. | 17071605 | 2006 |