Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.020 Biomarker disease BEFREE <b>Conclusion:</b> Standard <sup>18</sup>F-FDG PET/CT is an effective preoperative imaging method for the prediction of LN status in VC, allowing the prediction of pathologically negative groins and thus the selection of patients suitable for minimally invasive surgery. 28546331 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE Carcinoma of the vulva: HPV and p53 mutations. 8183560 1994
Entrez Id: 2946
Gene Symbol: GSTM2
GSTM2
0.010 GeneticVariation disease BEFREE Glutathione S-transferase M1 genotypes and the risk of vulvar cancer: a population-based case-control study. 10472942 1999
Entrez Id: 7180
Gene Symbol: CRISP2
CRISP2
0.010 PosttranslationalModification disease BEFREE TSP-1 hypermethylation was related to recurrence in patients with vulvar cancer. 20734389 2011
Entrez Id: 203074
Gene Symbol: PRSS55
PRSS55
0.010 PosttranslationalModification disease BEFREE TSP-1 hypermethylation was related to recurrence in patients with vulvar cancer. 20734389 2011
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.010 PosttranslationalModification disease BEFREE TSP-1 hypermethylation was related to recurrence in patients with vulvar cancer. 20734389 2011
Entrez Id: 84654
Gene Symbol: SPZ1
SPZ1
0.010 PosttranslationalModification disease BEFREE TSP-1 hypermethylation was related to recurrence in patients with vulvar cancer. 20734389 2011
Entrez Id: 7122
Gene Symbol: CLDN5
CLDN5
0.010 Biomarker disease BEFREE Claudin 5 does not seem to be important in VIN or vulvar carcinoma. 22170432 2012
Entrez Id: 1366
Gene Symbol: CLDN7
CLDN7
0.010 Biomarker disease BEFREE Claudin 1 and claudin 3S expressions also showed the same decreasing tendency from VIN towards vulvar carcinoma. 22170432 2012
Entrez Id: 9076
Gene Symbol: CLDN1
CLDN1
0.010 Biomarker disease BEFREE Claudin 1 and claudin 3S expressions also showed the same decreasing tendency from VIN towards vulvar carcinoma. 22170432 2012
Entrez Id: 6093
Gene Symbol: ROCK1
ROCK1
0.010 Biomarker disease BEFREE Rho-associated coiled-coil-containing protein kinase 1 (ROCK1) has been implicated in many cellular processes, but its function in vulvar cancer has never been examined. 25380619 2014
Entrez Id: 28
Gene Symbol: ABO
ABO
0.010 Biomarker disease BEFREE ABO blood groups as a prognostic factor for recurrence in ovarian and vulvar cancer. 29596526 2018
Entrez Id: 3048
Gene Symbol: HBG2
HBG2
0.010 GeneticVariation disease BEFREE A 47-year-old female with medical history of vulvar cancer and HIV undergoing chemoradiation was sent by the oncology clinic to the emergency department for worsening dyspnea, fatigue, hypoxia to 78% on room air, and gradual onset of cyanosis over the past week.A methemoglobin (MetHb) level was 49%. 27754990 2018
Entrez Id: 7095
Gene Symbol: SEC62
SEC62
0.010 Biomarker disease BEFREE All cases of VIN and vulvar cancer were Sec62/Ki67 and p16/Ki67 dual-stain positive, and normal and low-grade squamous intraepithelial lesions were all negative. 30607586 2019
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.020 Biomarker disease BEFREE All eight VIN were multifocal and had multicentric disease (CIN/VAIN) including one case that progressed to vulvar carcinoma. 16300821 2006
Entrez Id: 10970
Gene Symbol: CKAP4
CKAP4
0.010 AlteredExpression disease BEFREE Also, it is plausible that the evaluation of p63 expression in vulvar cancer at the biopsy level may bring important contribution on prognostic establishment and in elaborating better surgical approaches for vulvar cancer patients. 27359057 2016
Entrez Id: 6121
Gene Symbol: RPE65
RPE65
0.010 AlteredExpression disease BEFREE Also, it is plausible that the evaluation of p63 expression in vulvar cancer at the biopsy level may bring important contribution on prognostic establishment and in elaborating better surgical approaches for vulvar cancer patients. 27359057 2016
Entrez Id: 7405
Gene Symbol: UVRAG
UVRAG
0.010 AlteredExpression disease BEFREE Also, it is plausible that the evaluation of p63 expression in vulvar cancer at the biopsy level may bring important contribution on prognostic establishment and in elaborating better surgical approaches for vulvar cancer patients. 27359057 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.010 GeneticVariation disease BEFREE Although various studies showed a certain association between genes encoding the IL-1 family and human malignancies, no data with respect to vulvar cancer have been published to date. 14984963 2004
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.010 GeneticVariation disease BEFREE Although various studies showed a certain association between genes encoding the IL-1 family and human malignancies, no data with respect to vulvar cancer have been published to date. 14984963 2004
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.010 GeneticVariation disease BEFREE Cervical and vulvar cancer risk in relation to the joint effects of cigarette smoking and genetic variation in interleukin 2. 18628433 2008
Entrez Id: 1365
Gene Symbol: CLDN3
CLDN3
0.010 AlteredExpression disease BEFREE Changes in claudin 1 and claudin 3 expression during progression from VIN to vulvar carcinoma suggests a connection with claudin expression and differentiation of vulvar squamous cells. 22170432 2012
Entrez Id: 440900
Gene Symbol: LINC01191
LINC01191
0.040 AlteredExpression disease BEFREE Changes in claudin 1 and claudin 3 expression during progression from VIN to vulvar carcinoma suggests a connection with claudin expression and differentiation of vulvar squamous cells. 22170432 2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.030 Biomarker disease BEFREE Decreased survival in EGFR gene amplified vulvar carcinoma. 18768215 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE Does p53 codon 72 polymorphism have a prognostic value in carcinoma of the vulva and vagina? 28144815 2017