Gene: PALB2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in patients at high risk for hereditary breast cancer. 27783279 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients. 28281021 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families. 26534844 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 GeneticVariation disease CLINVAR A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer. 27067391 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes in Patients Lacking Known BRCA Mutations. 26898890 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Haplotype analyses of the c.1027C>T and c.2167_2168delAT recurrent truncating mutations in the breast cancer-predisposing gene PALB2. 27624329 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 GeneticVariation disease CLINVAR Protein-truncating variants in moderate-risk breast cancer susceptibility genes: a meta-analysis of high-risk case-control screening studies. 26250988 2015
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. 26315354 2015
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Integrated analysis of germline and somatic variants in ovarian cancer. 24448499 2014
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo. 24556926 2014
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 GeneticVariation disease CLINVAR Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients. 24763289 2014
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Breast-cancer risk in families with mutations in PALB2. 25099575 2014
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Hi-Plex for high-throughput mutation screening: application to the breast cancer susceptibility gene PALB2. 24206657 2013
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families. 23448497 2013
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 GeneticVariation disease CLINVAR Prevalence of PALB2 mutations in breast cancer patients in multi-ethnic Asian population in Malaysia and Singapore. 23977390 2013
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer. 21409391 2011
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR PALB2 mutations in familial breast and pancreatic cancer. 21365267 2011
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer. 21618343 2011
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer. 21285249 2011
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR PALB2 mutations in German and Russian patients with bilateral breast cancer. 21165770 2011
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR A PALB2 mutation associated with high risk of breast cancer. 21182766 2010
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR A PALB2 germline mutation associated with hereditary breast cancer in Italy. 19763884 2010
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. 19264984 2009
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		0.460 CausalMutation disease CLINVAR Structural basis for recruitment of BRCA2 by PALB2. 19609323 2009