Gene: HES1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3280
Gene Symbol: HES1
HES1 		0.030 AlteredExpression disease BEFREE Restoring the NOTCH pathway by lentiviral expression of NICD1 or HES1 in STRAP-depleted tumor cells reversed the CSC phenotype. 28827371 2017
Entrez Id: 3280
Gene Symbol: HES1
HES1 		0.030 AlteredExpression disease BEFREE The effects of ADAM17 inhibition on the CSC phenotype and chemosensitivity to 5-fluorouracil (5-FU) in CRC cells were examined. siRNA knockdown and TAPI-2 decreased the protein levels of cleaved Notch1 (Notch1 intracellular domain) and HES-1 in CRC cells. 26744411 2016
Entrez Id: 3280
Gene Symbol: HES1
HES1 		0.030 Biomarker disease BEFREE Furthermore, we demonstrated that inhibition of a Notch downstream target, Hes1, led to suppression of CSC phenotype in the TNFα-exposed cells. 22728043 2012