×
Entrez Id:
2
Gene Symbol:
A2M
A2M
0.300
Biomarker
disease
CTD_human
Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms.
15023809
2004
×
Entrez Id:
2
Gene Symbol:
A2M
A2M
0.300
Biomarker
disease
CTD_human
Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.
9811940
1998
×
Entrez Id:
2
Gene Symbol:
A2M
A2M
0.300
Biomarker
disease
CTD_human
Alpha-2 macroglobulin is genetically associated with Alzheimer disease.
9697696
1998
×
Entrez Id:
20
Gene Symbol:
ABCA2
ABCA2
0.030
GeneticVariation
disease
BEFREE
Recently, a single nucleotide polymorphism (SNP) in Abca2 was linked to early onset Alzheimer's disease (AD ).
18348684
2008
×
Entrez Id:
20
Gene Symbol:
ABCA2
ABCA2
0.030
Biomarker
disease
BEFREE
ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease .
15649702
2005
×
Entrez Id:
20
Gene Symbol:
ABCA2
ABCA2
0.030
GeneticVariation
disease
BEFREE
Recently genetic variation in the DAPK1 and ABCA2 genes has been reported to be associated with late- and early-onset Alzheimer's disease (AD ), respectively.
18336955
2009
×
Entrez Id:
10347
Gene Symbol:
ABCA7
ABCA7
0.320
Biomarker
disease
CTD_human
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
21460840
2011
×
Entrez Id:
10347
Gene Symbol:
ABCA7
ABCA7
0.320
Biomarker
disease
BEFREE
Pathogenic variants in the autosomal dominant genes PSEN1, PSEN2, or APP, APOE4 alleles, and rare variants within TREM2, SORL1, and ABCA7 contribute to early-onset Alzheimer's disease (EOAD ).
31381512
2019
×
Entrez Id:
10347
Gene Symbol:
ABCA7
ABCA7
0.320
GeneticVariation
disease
BEFREE
Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease .
28447221
2017
×
Entrez Id:
10347
Gene Symbol:
ABCA7
ABCA7
0.320
Biomarker
disease
CTD_human
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease.
25807283
2015
×
Entrez Id:
51225
Gene Symbol:
ABI3
ABI3
0.300
Biomarker
disease
CTD_human
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
28714976
2017
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.300
Biomarker
disease
CTD_human
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.
17192785
2007
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.300
Biomarker
disease
CTD_human
Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population.
10643899
1999
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.300
Biomarker
disease
CTD_human
Alzheimer disease risk and genetic variation in ACE: a meta-analysis.
14872014
2004
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.300
Biomarker
disease
CTD_human
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
30820047
2019
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
0.300
Biomarker
disease
CTD_human
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
9916793
1999
×
Entrez Id:
43
Gene Symbol:
ACHE
ACHE
0.300
Biomarker
disease
CTD_human
Characterisation of acetylcholinesterase release from neuronal cells.
23047022
2013
×
Entrez Id:
43
Gene Symbol:
ACHE
ACHE
0.300
Biomarker
disease
CTD_human
Lithium treatment induces proteasomal degradation of over-expressed acetylcholinesterase (AChE-S) and inhibit GSK3β.
22944069
2013
×
Entrez Id:
102
Gene Symbol:
ADAM10
ADAM10
0.300
Biomarker
disease
CTD_human
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
30820047
2019
×
Entrez Id:
9510
Gene Symbol:
ADAMTS1
ADAMTS1
0.300
Biomarker
disease
CTD_human
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
30820047
2019
×
Entrez Id:
8540
Gene Symbol:
AGPS
AGPS
0.010
Biomarker
disease
BEFREE
However, deterioration was significantly faster when using the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS -Cog) over 3 years in participants with EOAD than in those with LOAD; hence, prediction models for the mean ADAS -Cog trajectories are presented.
28859660
2017
×
Entrez Id:
267
Gene Symbol:
AMFR
AMFR
0.300
Biomarker
disease
CTD_human
Autocrine motility factor receptor is involved in the process of learning and memory in the central nervous system.
22313999
2012
×
Entrez Id:
301
Gene Symbol:
ANXA1
ANXA1
0.010
Biomarker
disease
BEFREE
Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease .
15917097
2005
×
Entrez Id:
322
Gene Symbol:
APBB1
APBB1
0.010
GeneticVariation
disease
BEFREE
A risk for early-onset Alzheimer's disease associated with the APBB1 gene (FE65 ) intron 13 polymorphism.
12727304
2003
×
Entrez Id:
338
Gene Symbol:
APOB
APOB
0.010
GeneticVariation
disease
BEFREE
Collectively, these novel findings highlight the important role of LDL-C in EOAD pathogenesis and suggest a direct link of APOB variants to AD risk.
31135820
2019