Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1 		0.300 Biomarker phenotype CTD_human α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage. 24133248 2013
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Therapeutic phenotype CTD_human Interleukin-1 receptor antagonist ameliorates neonatal lipopolysaccharide-induced long-lasting hyperalgesia in the adult rats. 20937348 2011
Entrez Id: 6678
Gene Symbol: SPARC
SPARC 		0.300 Biomarker phenotype CTD_human Behavioral signs of chronic back pain in the SPARC-null mouse. 20714283 2011
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1 		0.300 Biomarker phenotype CTD_human Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation. 21481532 2011
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Biomarker phenotype CTD_human Interleukin-1 receptor antagonist ameliorates neonatal lipopolysaccharide-induced long-lasting hyperalgesia in the adult rats. 20937348 2011
Entrez Id: 3231
Gene Symbol: HOXD1
HOXD1 		0.300 Biomarker phenotype CTD_human An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. 21151121 2011
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		0.300 Biomarker phenotype CTD_human Sex differences in behavior and expression of CGRP-related genes in a rodent model of chronic migraine. 21521205 2011
Entrez Id: 9607
Gene Symbol: CARTPT
CARTPT 		0.300 Therapeutic phenotype CTD_human Evidence for the participation of cocaine- and amphetamine-regulated transcript peptide (CART) in the fluoxetine-induced anti-hyperalgesia in neuropathic rats. 21167239 2011
Entrez Id: 815
Gene Symbol: CAMK2A
CAMK2A 		0.300 Biomarker phenotype CTD_human Ca2+/calmodulin-dependent protein kinase II alpha is required for the initiation and maintenance of opioid-induced hyperalgesia. 20053885 2010
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5 		0.300 Biomarker phenotype CTD_human A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators. 20086212 2010
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
Entrez Id: 4157
Gene Symbol: MC1R
MC1R 		0.300 Biomarker phenotype CTD_human Sex-specific mediation of opioid-induced hyperalgesia by the melanocortin-1 receptor. 19996949 2010
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE 		0.300 Biomarker phenotype CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222 2010
Entrez Id: 1814
Gene Symbol: DRD3
DRD3 		0.300 Biomarker phenotype CTD_human Dopamine D3 receptor regulates basal but not amphetamine-induced changes in pain sensitivity in mice. 20433900 2010
Entrez Id: 4803
Gene Symbol: NGF
NGF 		0.300 Biomarker phenotype CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222 2010
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.300 Biomarker phenotype CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222 2010
Entrez Id: 5368
Gene Symbol: PNOC
PNOC 		0.300 Biomarker phenotype CTD_human Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. 19231294 2009
Entrez Id: 8912
Gene Symbol: CACNA1H
CACNA1H 		0.300 Biomarker phenotype CTD_human In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy. 19577366 2009
Entrez Id: 5024
Gene Symbol: P2RX3
P2RX3 		0.300 Biomarker phenotype CTD_human Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy. 19383439 2009
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B 		0.300 Biomarker phenotype CTD_human Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine. 20042082 2009
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2 		0.300 Biomarker phenotype CTD_human Bradykinin receptors antagonists and nitric oxide synthase inhibitors in vincristine and streptozotocin induced hyperalgesia in chemotherapy and diabetic neuropathy rat model. 19300402 2009
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1 		0.300 Biomarker phenotype CTD_human Bradykinin receptors antagonists and nitric oxide synthase inhibitors in vincristine and streptozotocin induced hyperalgesia in chemotherapy and diabetic neuropathy rat model. 19300402 2009
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker phenotype CTD_human Role of ET(A) and ET(B) endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats. 19429182 2009
Entrez Id: 5582
Gene Symbol: PRKCG
PRKCG 		0.300 Biomarker phenotype CTD_human Systemic lidocaine inhibits remifentanil-induced hyperalgesia via the inhibition of cPKCgamma membrane translocation in spinal dorsal horn of rats. 19955894 2009