Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
0.740 CausalMutation disease CLINVAR
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
0.740 Biomarker disease CTD_human
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.300 Biomarker disease CTD_human
Entrez Id: 8643
Gene Symbol: PTCH2
PTCH2
0.300 Biomarker disease CTD_human
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.300 Biomarker disease CTD_human
Entrez Id: 6659
Gene Symbol: SOX4
SOX4
0.010 AlteredExpression disease BEFREE Sox4 and Sox11 were strongly expressed in most classical medulloblastomas but only weakly in desmoplastic medulloblastomas. 12125983 2002
Entrez Id: 92335
Gene Symbol: STRADA
STRADA
0.300 Biomarker disease CTD_human A sensitized RNA interference screen identifies a novel role for the PI3K p110γ isoform in medulloblastoma cell proliferation and chemoresistance. 21652733 2011
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
0.300 Biomarker disease CTD_human A sensitized RNA interference screen identifies a novel role for the PI3K p110γ isoform in medulloblastoma cell proliferation and chemoresistance. 21652733 2011
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
0.010 AlteredExpression disease BEFREE Among the 17q23 genes, RPS6KB1 showed markedly elevated transcript levels as compared to normal cerebellum in five of six DMBs and four of five classic medulloblastomas investigated. 16400626 2006
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
0.320 Biomarker disease CTD_human Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice. 19155313 2009
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
0.300 Biomarker disease CTD_human Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice. 19155313 2009
Entrez Id: 6046
Gene Symbol: BRD2
BRD2
0.300 Biomarker disease CTD_human BET bromodomain protein inhibition is a therapeutic option for medulloblastoma. 24231268 2013
Entrez Id: 8019
Gene Symbol: BRD3
BRD3
0.300 Biomarker disease CTD_human BET bromodomain protein inhibition is a therapeutic option for medulloblastoma. 24231268 2013
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
0.300 Biomarker disease CTD_human BET bromodomain protein inhibition is a therapeutic option for medulloblastoma. 24231268 2013
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
0.320 Biomarker disease CTD_human Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma. 19213072 2009
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
0.320 Biomarker disease CTD_human Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. 18347096 2008
Entrez Id: 3090
Gene Symbol: HIC1
HIC1
0.300 Biomarker disease CTD_human Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. 18347096 2008
Entrez Id: 474
Gene Symbol: ATOH1
ATOH1
0.300 Biomarker disease CTD_human Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. 18347096 2008
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
0.010 Biomarker disease BEFREE Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes. 18924150 2009
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
0.010 GeneticVariation disease BEFREE Diagnostic challenges in a child with early onset desmoplastic medulloblastoma and homozygous variants in MSH2 and MSH6. 29302048 2018
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
0.010 GeneticVariation disease BEFREE Diagnostic challenges in a child with early onset desmoplastic medulloblastoma and homozygous variants in MSH2 and MSH6. 29302048 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.300 Biomarker disease CTD_human Double high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation for primary disseminated medulloblastoma: a report of 3 cases. 20168248 2010
Entrez Id: 6277
Gene Symbol: S100A6
S100A6
0.300 Biomarker disease CTD_human Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma. 17579622 2007
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
0.300 Biomarker disease CTD_human Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma. 17579622 2007
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
0.300 Biomarker disease CTD_human Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma. 17579622 2007