Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3394
Gene Symbol: IRF8
IRF8 		0.300 Biomarker disease CTD_human Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953 2009
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Therapeutic disease CTD_human Priapism following olanzapine administration in a patient with multiple sclerosis. 9664777 1998
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.300 Biomarker disease CTD_human Impact of cladribine on soluble adhesion molecules in multiple sclerosis. 20175758 2010
Entrez Id: 3575
Gene Symbol: IL7R
IL7R 		0.300 Biomarker disease CTD_human Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. 19525955 2009
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human "Accelerated evolution of brain atrophy and ""black holes"" in MS patients with APOE-epsilon 4." 15048896 2004
Entrez Id: 6401
Gene Symbol: SELE
SELE 		0.300 Biomarker disease CTD_human Impact of cladribine on soluble adhesion molecules in multiple sclerosis. 20175758 2010
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		0.300 Biomarker disease CTD_human "Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of ""Humanized"" Multiple Sclerosis-like Disease." 25911099 2015
Entrez Id: 923
Gene Symbol: CD6
CD6 		0.300 Biomarker disease CTD_human Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
Entrez Id: 3575
Gene Symbol: IL7R
IL7R 		0.300 Biomarker disease CTD_human Risk alleles for multiple sclerosis identified by a genomewide study. 17660530 2007
Entrez Id: 3766
Gene Symbol: KCNJ10
KCNJ10 		0.300 Biomarker disease CTD_human Enhanced accumulation of Kir4.1 protein, but not mRNA, in a murine model of cuprizone-induced demyelination. 24070676 2013
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		0.300 Biomarker disease CTD_human
Entrez Id: 5010
Gene Symbol: CLDN11
CLDN11 		0.300 Biomarker disease CTD_human "Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of ""Humanized"" Multiple Sclerosis-like Disease." 25911099 2015
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.300 Biomarker disease CTD_human Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis. 25458313 2015
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.300 Therapeutic disease CTD_human Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. 12432978 2002
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.300 Biomarker disease CTD_human Fraction of IL-10+ and IL-17+ CD8 T cells is increased in MS patients in remission and during a relapse, but is not influenced by immune modulators. 23517930 2013
Entrez Id: 3575
Gene Symbol: IL7R
IL7R 		0.300 Biomarker disease CTD_human Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. 17660816 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker disease CTD_human Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis. 25458313 2015
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.300 Biomarker disease CTD_human Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis. 25458313 2015
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA 		0.300 Biomarker disease CTD_human IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. 19119414 2009
Entrez Id: 958
Gene Symbol: CD40
CD40 		0.300 Biomarker disease CTD_human Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. 19525955 2009
Entrez Id: 3575
Gene Symbol: IL7R
IL7R 		0.300 Biomarker disease CTD_human Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. 17660817 2007
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A 		0.300 Biomarker disease CTD_human Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. 19525955 2009
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14 		0.300 Biomarker disease CTD_human Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.300 Therapeutic disease CTD_human Immune regulatory effects of high dose vitamin D3 supplementation in a randomized controlled trial in relapsing remitting multiple sclerosis patients receiving IFNβ; the SOLARIUM study. 27806875 2016
Entrez Id: 2638
Gene Symbol: GC
GC 		0.300 Biomarker disease CTD_human Increased circulating levels of vitamin D binding protein in MS patients. 25590278 2015