Gene: DGKK ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 GeneticVariation disease BEFREE Five DGKK variants previously reported as associated with hypospadias were identified in the genotype data. 31102501 2019
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 GeneticVariation disease BEFREE This study successfully implicated DGKK variants in hypospadias risk among a Han Chinese population, especially for mild/moderate cases. 28597849 2019
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 Biomarker disease BEFREE For some birth defects, including oral clefts and CHDs, several novel susceptibility loci have been identified and replicated through GWAS, including 8q24 for oral clefts, DGKK for hypospadias, and 4p16 for CHDs. 31654503 2019
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 GeneticVariation disease BEFREE Our study provides strong evidence of an association between DGKK nucleotide variants, haplotypes and hypospadias susceptibility. 29464676 2018
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 Biomarker disease CTD_human Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk. 27098078 2016
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 Biomarker disease BEFREE Our meta-analysis supports the hypothesis that DGKK is a common risk gene for hypospadias, particularly in cases of mild or moderate hypospadias in Caucasian populations. 25327554 2015
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 GeneticVariation disease GWASCAT Genome-wide association analyses identify variants in developmental genes associated with hypospadias. 25108383 2014
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 GeneticVariation disease BEFREE We examined the association of 27 DGKK single nucleotide polymorphisms with hypospadias relative to population based nonmalformed controls born in selected California counties from 1990 to 2003. 23177175 2013
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 GeneticVariation disease GWASDB Common variants in DGKK are strongly associated with risk of hypospadias. 21113153 2011
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 Biomarker disease BEFREE We propose DGKK as a major risk gene for hypospadias. 21113153 2011
Entrez Id: 139189
Gene Symbol: DGKK
DGKK 		0.470 Biomarker disease CTD_human Common variants in DGKK are strongly associated with risk of hypospadias. 21113153 2011