Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6440
Gene Symbol: SFTPC
SFTPC 		0.360 SusceptibilityMutation disease ORPHANET
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ 		0.010 Biomarker disease BEFREE <b>Abbreviations:</b> bCPAP: bubble continuous positive airway pressure; CPAP: continuous positive airway pressure; ELBW: extremely low birthweight; FiO<sub>2</sub>: ratio of oxygen content in gas flow (%); IbCPAP: improvised bubble continuous positive airway pressure device; LBW: low birthweight; NNU: neonatal unit; PEEP: positive end expiratory pressure; politeCPAP: the newly developed commercial bCPAP machine; RDS: respiratory distress syndrome; SpO<sub>2</sub>, oxygen saturation level (%). 30957682 2019
Entrez Id: 5961
Gene Symbol: PRPH2
PRPH2 		0.010 Biomarker disease BEFREE <b>Abbreviations:</b> bCPAP: bubble continuous positive airway pressure; CPAP: continuous positive airway pressure; ELBW: extremely low birthweight; FiO<sub>2</sub>: ratio of oxygen content in gas flow (%); IbCPAP: improvised bubble continuous positive airway pressure device; LBW: low birthweight; NNU: neonatal unit; PEEP: positive end expiratory pressure; politeCPAP: the newly developed commercial bCPAP machine; RDS: respiratory distress syndrome; SpO<sub>2</sub>, oxygen saturation level (%). 30957682 2019
Entrez Id: 7263
Gene Symbol: TST
TST 		0.010 Biomarker disease BEFREE <b>Abbreviations:</b> bCPAP: bubble continuous positive airway pressure; CPAP: continuous positive airway pressure; ELBW: extremely low birthweight; FiO<sub>2</sub>: ratio of oxygen content in gas flow (%); IbCPAP: improvised bubble continuous positive airway pressure device; LBW: low birthweight; NNU: neonatal unit; PEEP: positive end expiratory pressure; politeCPAP: the newly developed commercial bCPAP machine; RDS: respiratory distress syndrome; SpO<sub>2</sub>, oxygen saturation level (%). 30957682 2019
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease BEFREE Respiratory distress syndrome due to a novel homozygous ABCA3 mutation in a term neonate. 22707629 2011
Entrez Id: 3371
Gene Symbol: TNC
TNC 		0.010 AlteredExpression disease BEFREE Tenascin-C is highly expressed in respiratory distress syndrome and bronchopulmonary dysplasia. 11850444 2002
Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB 		0.400 GeneticVariation disease BEFREE Surfactant protein B polymorphism and respiratory distress syndrome in premature twins. 12483294 2003
Entrez Id: 2335
Gene Symbol: FN1
FN1 		0.010 Biomarker disease BEFREE Fibronectin: role in respiratory distress syndrome and bronchopulmonary dysplasia. 1514107 1992
Entrez Id: 387129
Gene Symbol: NPSR1
NPSR1 		0.010 Biomarker disease BEFREE G protein-coupled receptor for asthma susceptibility associates with respiratory distress syndrome. 16938805 2006
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.010 GeneticVariation disease BEFREE Glutathione-S-transferase-P1 I105V polymorphism and response to antenatal betamethasone in the prevention of respiratory distress syndrome. 19183974 2009
Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB 		0.400 GeneticVariation disease BEFREE Surfactant protein B gene polymorphism in preterm babies with respiratory distress syndrome. 21180884 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.040 GeneticVariation disease BEFREE ACE gene polymorphism in premature neonates with respiratory distress syndrome. 21749216 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.010 GeneticVariation disease BEFREE Endothelial NOS gene Glu298Asp polymorphism in preterm neonates with respiratory distress syndrome. 23359565 2013
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 Biomarker disease BEFREE ABCA3 deficiency should be considered in mature babies who develop severe respiratory distress syndrome. 24269975 2014
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4 		0.020 GeneticVariation disease BEFREE ATP-binding cassette transporter A3 (ABCA3) mutation in a late preterm with respiratory distress syndrome. 25031143 2014
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD 		0.040 Biomarker disease BEFREE SP-D has been implicated in the development of respiratory diseases including respiratory distress syndrome, bronchopulmonary dysplasia, allergic asthma, and chronic obstructive pulmonary disease. 29473039 2018
Entrez Id: 4153
Gene Symbol: MBL2
MBL2 		0.010 GeneticVariation disease BEFREE MBL2 variant-type and mannose-binding lectin deficiency are important risk factors for respiratory distress syndrome development in preterm infants. 31029683 2019
Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB 		0.400 Biomarker disease BEFREE A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome. 28465315 2017
Entrez Id: 6440
Gene Symbol: SFTPC
SFTPC 		0.360 Biomarker disease BEFREE A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome. 28465315 2017
Entrez Id: 83640
Gene Symbol: RAMAC
RAMAC 		0.010 Biomarker disease BEFREE A randomized trial comparing the short binasal prong to the RAM cannula for noninvasive ventilation support of preterm infants with respiratory distress syndrome. 31394948 2019
Entrez Id: 137196
Gene Symbol: CCDC26
CCDC26 		0.010 Biomarker disease BEFREE A randomized trial comparing the short binasal prong to the RAM cannula for noninvasive ventilation support of preterm infants with respiratory distress syndrome. 31394948 2019
Entrez Id: 5873
Gene Symbol: RAB27A
RAB27A 		0.010 Biomarker disease BEFREE A randomized trial comparing the short binasal prong to the RAM cannula for noninvasive ventilation support of preterm infants with respiratory distress syndrome. 31394948 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 GeneticVariation disease BEFREE Association between Interleukin-10-1082 G/A and Tumor Necrosis Factor-<b>α</b> 308 G/A Gene Polymorphisms and Respiratory Distress Syndrome in Iranian Preterm Infants. 28298812 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 GeneticVariation disease BEFREE Association between interleukin-10 genetic variant (-1082G>A) with detection and severity of respiratory distress syndrome in preterm neonates. 31478351 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.010 GeneticVariation disease BEFREE Association between Interleukin-10-1082 G/A and Tumor Necrosis Factor-<b>α</b> 308 G/A Gene Polymorphisms and Respiratory Distress Syndrome in Iranian Preterm Infants. 28298812 2017