Gene: GABPA ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 AlteredExpression group BEFREE Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function. 31706979 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE Thus, Nrf2 is a promising target for anti-aging strategies to combat age-related heart diseases, such as age-related cardiomyopathy. 31712965 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE The protein-protein interaction (PPI) of Keap1-Nrf2 is implicated in several neurodegenerative diseases like cancer, diabetes, and cardiomyopathy. 31726716 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE Effects of PP2A/Nrf2 on experimental diabetes mellitus-related cardiomyopathy by regulation of autophagy and apoptosis through ROS dependent pathway. 31173878 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE ZJ01 was identified as a new Keap1-Nrf2 PPI inhibitor and drug lead for septic cardiomyopathy treatment by in vitro and in vivo experiments. 29693453 2018
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 AlteredExpression group BEFREE Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice. 30096613 2018
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE Nrf2-KO mice are susceptible, and Nrf2-TG mice are resistant, respectively, to Ang II-induced cardiomyopathy. 29353218 2018
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE Elucidation of protective efficacy of Pentahydroxy flavone isolated from Madhuca indica against arsenite-induced cardiomyopathy: Role of Nrf-2, PPAR-γ, c-fos and c-jun. 28942082 2017
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE Intermittent hypoxia-induced cardiomyopathy and its prevention by Nrf2 and metallothionein. 28778483 2017
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		0.100 Biomarker group BEFREE In transcription factor assays, we further demonstrate increased binding of Nrf2 to ARE during the development of cardiomyopathy. 21126175 2011