Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 32
Gene Symbol: ACACB
ACACB 		0.300 Biomarker phenotype CTD_human Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome. 22658938 2012
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Therapeutic phenotype CTD_human Adiponectin upregulates ferritin heavy chain in skeletal muscle cells. 18931039 2009
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Therapeutic phenotype CTD_human Dual acting and pan-PPAR activators as potential anti-diabetic therapies. 21484566 2011
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		0.300 Biomarker phenotype CTD_human The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker. 19034036 2008
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.300 Biomarker phenotype CTD_human Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice. 25734695 2015
Entrez Id: 367
Gene Symbol: AR
AR 		0.300 Biomarker phenotype CTD_human Androgen receptor CAG repeat length polymorphism modifies the impact of testosterone on insulin sensitivity in men. 21444647 2011
Entrez Id: 718
Gene Symbol: C3
C3 		0.300 Biomarker phenotype CTD_human Sex steroid hormones induce acylation stimulating protein resistance in 3T3-L1 adipocytes. 18615583 2008
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.300 Biomarker phenotype CTD_human Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans. 22325453 2012
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 9332
Gene Symbol: CD163
CD163 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 948
Gene Symbol: CD36
CD36 		0.300 Biomarker phenotype CTD_human Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension. 14640889 2003
Entrez Id: 958
Gene Symbol: CD40
CD40 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 968
Gene Symbol: CD68
CD68 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 1363
Gene Symbol: CPE
CPE 		0.300 Biomarker phenotype CTD_human The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. 15358678 2004
Entrez Id: 1489
Gene Symbol: CTF1
CTF1 		0.300 Biomarker phenotype CTD_human Cardiotrophin-1 is a key regulator of glucose and lipid metabolism. 21803294 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.300 Biomarker phenotype CTD_human Among the ErbB family members, only ErbB1 expression was correlated with insulin sensitivity. 22238402 2012
Entrez Id: 9965
Gene Symbol: FGF19
FGF19 		0.200 Biomarker phenotype CTD_mouse The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis. 28673684 2017
Entrez Id: 2688
Gene Symbol: GH1
GH1 		0.300 Biomarker phenotype CTD_human Insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load. 21559284 2011
Entrez Id: 2778
Gene Symbol: GNAS
GNAS 		0.300 Biomarker phenotype CTD_human The CC genotype of the GNAS T393C polymorphism is associated with obesity and insulin resistance in women with polycystic ovary syndrome. 17062894 2006
Entrez Id: 2878
Gene Symbol: GPX3
GPX3 		0.300 Biomarker phenotype CTD_human Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. 19270708 2009
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1 		0.300 Biomarker phenotype CTD_human A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components. 23512162 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Therapeutic phenotype CTD_human Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. 18375438 2008
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker phenotype CTD_human Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. 18375438 2008
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Therapeutic phenotype CTD_human This study demonstrates that HO-1 induction improves insulin sensitivity, downregulates the peripheral endocannabinoid system, reduces adipose tissue volume, and causes adipose tissue remodeling in a model of obesity-induced insulin resistance. 19171794 2009
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker phenotype CTD_human This study demonstrates that HO-1 induction improves insulin sensitivity, downregulates the peripheral endocannabinoid system, reduces adipose tissue volume, and causes adipose tissue remodeling in a model of obesity-induced insulin resistance. 19171794 2009