Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
0.050 GeneticVariation group BEFREE <b>Objectives:</b> The present study is geared to learning about the patterns of tau seeding and cells involved following unilateral inoculation in the corpus callosum of homogenates from sporadic Alzheimer's disease (AD), primary age-related tauopathy (PART: neuronal 4Rtau and 3Rtau), pure aging-related tau astrogliopathy (ARTAG: astroglial 4Rtau with thorn-shaped astrocytes TSAs), globular glial tauopathy (GGT: 4Rtau with neuronal tau and specific tau inclusions in astrocytes and oligodendrocytes, GAIs and GOIs, respectively), progressive supranuclear palsy (PSP: 4Rtau with neuronal inclusions, tufted astrocytes and coiled bodies), Pick's disease (PiD: 3Rtau with characteristic Pick bodies in neurons and tau containing fibrillar astrocytes), and frontotemporal lobar degeneration linked to P301L mutation (FTLD-P301L: 4Rtau familial tauopathy). 31191295 2019
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
0.050 Biomarker group BEFREE PSP is a pathologically defined neurodegenerative tauopathy with a variety of clinical presentations including typical Richardson's syndrome and other variant PSP syndromes. 28500751 2017
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
0.050 Biomarker group BEFREE Over two dozen mutations in the gene encoding the microtubule associated protein tau cause a variety of neurodegenerative dementias known as tauopathies, including frontotemporal dementia (FTD), PSP, CBD and Pick's disease. 24086739 2013
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
0.050 Biomarker group BEFREE Further immunohistochemical and biochemical studies revealed that AgD is a four-repeat (4R) tauopathy similar to PSP and corticobasal degeneration (CBD), but distinct from Alzheimer's disease (AD) and Pick's disease. 15641585 2004
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
0.050 Biomarker group BEFREE Some of the sporadic disorders (progressive supranuclear palsy [PSP] and corticobasal degeneration) have been referred to by molecular pathologists as primary tauopathies, implicating abnormalities of tau in their pathogenesis. 14502653 2003