Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.300 Biomarker disease CTD_human Oxpentifylline inhibits tumor necrosis factor-alpha mRNA transcription and protects against arthritis in mercuric chloride-treated brown Norway rats. 7589090 1995
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.300 Therapeutic disease CTD_human Oxpentifylline inhibits tumor necrosis factor-alpha mRNA transcription and protects against arthritis in mercuric chloride-treated brown Norway rats. 7589090 1995
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.300 Biomarker disease CTD_human Effect of capsaicin on substance P and nerve growth factor in adjuvant arthritic rats. 9259450 1997
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.300 Biomarker disease CTD_human The effect of thalidomide and 2 analogs on collagen induced arthritis. 9598899 1998
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.300 Biomarker disease CTD_human The effect of thalidomide and 2 analogs on collagen induced arthritis. 9598899 1998
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.300 Therapeutic disease CTD_human Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA). 10444273 1999
Entrez Id: 3596
Gene Symbol: IL13
IL13
0.300 Therapeutic disease CTD_human Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA). 10444273 1999
Entrez Id: 969
Gene Symbol: CD69
CD69
0.300 Biomarker disease CTD_human CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. 12882836 2003
Entrez Id: 2209
Gene Symbol: FCGR1A
FCGR1A
0.200 Biomarker disease CTD_mouse FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis. 12875993 2003
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.300 Biomarker disease CTD_human Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice. 15142272 2004
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.300 Biomarker disease CTD_human Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. 15188379 2004
Entrez Id: 6772
Gene Symbol: STAT1
STAT1
0.300 Biomarker disease CTD_human Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. 15188379 2004
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
0.300 Biomarker disease CTD_human Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis. 16200597 2005
Entrez Id: 6288
Gene Symbol: SAA1
SAA1
0.300 Biomarker disease CTD_human Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition. 15944321 2005
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. 16713974 2006
Entrez Id: 796
Gene Symbol: CALCA
CALCA
0.300 Biomarker disease CTD_human Changes in dorsal root ganglion CGRP expression in a chronic inflammatory model of the rat knee joint: differential modulation by rofecoxib and paracetamol. 16690336 2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.300 Biomarker disease CTD_human Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis. 17827786 2007
Entrez Id: 2182
Gene Symbol: ACSL4
ACSL4
0.300 Biomarker disease CTD_human Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis. 18988084 2008
Entrez Id: 5734
Gene Symbol: PTGER4
PTGER4
0.300 Biomarker disease CTD_human MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. 18287210 2008
Entrez Id: 51703
Gene Symbol: ACSL5
ACSL5
0.300 Biomarker disease CTD_human Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis. 18988084 2008
Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
0.300 Biomarker disease CTD_human Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis. 18988084 2008
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.300 Biomarker disease CTD_human Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins. 19330884 2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.300 Biomarker disease CTD_human Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins. 19330884 2009
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.300 Biomarker disease CTD_human Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins. 19330884 2009