Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
0.030 GeneticVariation disease BEFREE IFNγ-deficient mice did not develop features of MAS when treated with repeated doses of either the TLR-9 agonist or IFNγ alone. 30073799 2019
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
0.030 Biomarker disease BEFREE Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in mice. 29295842 2018
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
0.030 Biomarker disease BEFREE Despite their ability to produce this anti-inflammatory cytokine, IL-10<sup>+</sup> hepatic CD8<sup>+</sup> T cells in TLR9-MAS mice did not resemble CD8<sup>+</sup> T suppressor cells. 28034913 2017