Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.060 AlteredExpression disease BEFREE PTGS2 expression and PGE(2) biosynthesis is elevated in endometrial adenocarcinoma, however the mechanism whereby PTGS and PGE(2) regulate endometrial tumour growth is unknown. 21589857 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.060 AlteredExpression disease BEFREE In the present study, we investigated the effect of PGE(2) and PGF(2alpha) on the expression of COX-2 via the FP receptor in endometrial adenocarcinoma cells stably expressing the FP receptor (FPS cells). 18316157 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.060 AlteredExpression disease BEFREE Finally, we have shown that PGF2alpha could potentiate tumorigenesis in endometrial adenocarcinoma explants by inducing the expression of COX-2 mRNA. 16081631 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.060 Biomarker disease BEFREE These observations prompted us to examine whether the COX-2-PPARdelta signaling pathway is also involved during development of uterine adenocarcinoma. 11228540 2002
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.060 AlteredExpression disease BEFREE Expression of COX-2 and PGE synthase and synthesis of PGE(2)in endometrial adenocarcinoma: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors. 11592775 2001
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.060 AlteredExpression disease BEFREE Expression of cyclooxygenase 2 by prostaglandin E(2) in human endometrial adenocarcinoma cell line HEC-1B. 10952941 2000