Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2157
Gene Symbol: F8
F8
0.060 GeneticVariation disease BEFREE VWD3 platelets seem to compensate for the FVIII-associated reduction in TG by their exposure of P-selectin and phosphatidylserine. 30836803 2020
Entrez Id: 2157
Gene Symbol: F8
F8
0.060 GeneticVariation disease BEFREE Forty-five patients were enrolled in each group; 71 % of PBWD had a severe form of the bleeding disorder (FVIII/IX activity < 1 % or VWD type 3), and 60 % of all PWBD were treated on-demand. 30261520 2018
Entrez Id: 2157
Gene Symbol: F8
F8
0.060 AlteredExpression disease BEFREE Forty-five patients were enrolled in each group; 71 % of PBWD had a severe form of the bleeding disorder (FVIII/IX activity < 1 % or VWD type 3), and 60 % of all PWBD were treated on-demand. 28692112 2017
Entrez Id: 2157
Gene Symbol: F8
F8
0.060 Biomarker disease BEFREE The aim of this study was to evaluate the effect of VWF-FVIII concentrate treatment in VWD-3 patients with the Total Thrombus Analysis System (T-TAS<sup>®</sup>), which measures thrombus formation under flow conditions. 27761577 2017
Entrez Id: 2157
Gene Symbol: F8
F8
0.060 Biomarker disease BEFREE A total absence of FVIII:C has never been reported in type 3 VWD. 19563498 2009
Entrez Id: 2157
Gene Symbol: F8
F8
0.060 AlteredExpression disease BEFREE The BT is normal and FVIII:C levels clearly are lower than vWF:Ag in type 2N vWD. 16276467 2005