| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | Immunohistochemical analysis showed immunoreactivity for MUC4 and break-apart fluorescence in situ hybridization was positive for FUS rearrangement, confirming the diagnosis of LGFMS. | 30632203 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Low-grade fibromyxoid sarcoma (LGFMS) and sclerosing epithelioid fibrosarcoma (SEF) are rare tumors with distinct sets of morphological features, both characterized by MUC4 immunoreactivity. | 29426275 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Hyalinized spindle cell tumor with giant rosettes (HSCTGR) is a morphological variant of LGFMS that shares the same balanced translocation, and is also immunoreactive for MUC4. | 28648941 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | The results of immunohistochemistry (MUC4 staining) and FUS gene rearrangement by fluorescence in situ hybridization confirmed the diagnosis of LGFMS. | 28558780 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | Both can occur superficially; and whereas MUC4 immunoreactivity is characteristic of LGFMS, this can also be seen in some OFMTs. | 25532939 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | All but one pure SEF and all hybrid SEF/LGFMS-tested cases showed MUC4 immunoreactivity. | 25231134 | 2015 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | MUC4 has recently been identified as a sensitive and specific marker for LGFMS; MUC4 expression was also observed in 2 tumors with hybrid features of SEF and LGFMS. | 22982887 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | All 49 LGFMS cases (100%) showed cytoplasmic staining for MUC4, which was usually diffuse and intense. | 21415703 | 2011 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Gene expression analysis clearly distinguished LGFMS from morphologically similar tumors and MUC4 was identified as a potential diagnostic marker for LGFMS by gene expression and IHC analysis. | 21536545 | 2011 |