Gene: IRF4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3662
Gene Symbol: IRF4
IRF4 		0.040 Biomarker disease BEFREE An essential IKZF1-IRF4-MYC axis has recently been proposed to underlie the toxicity of IMiDs in PEL. 29954751 2018
Entrez Id: 3662
Gene Symbol: IRF4
IRF4 		0.040 AlteredExpression disease BEFREE Primary effusion lymphoma (PEL), strongly linked with latent infection of Kaposi's sarcoma-associated herpesvirus (KSHV), constitutively expresses cellular interferon regulatory factor 4 (IRF4) while suppressing the expression of B cell lymphoma 6 (BCL6). 29397940 2018
Entrez Id: 3662
Gene Symbol: IRF4
IRF4 		0.040 Biomarker disease BEFREE Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors. 26119939 2016
Entrez Id: 3662
Gene Symbol: IRF4
IRF4 		0.040 AlteredExpression disease BEFREE Comparison of MUM1/IRF4 expression with that of other histogenetic markers defined two phenotypic variants of PEL, i.e. 11091208 2000