Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | An essential IKZF1-IRF4-MYC axis has recently been proposed to underlie the toxicity of IMiDs in PEL. | 29954751 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors. | 26119939 | 2016 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Treatment of PEL cell lines with BET inhibitors suppressed the expression of MYC and resulted in a genome-wide perturbation of MYC-dependent genes. | 23792448 | 2014 | ||||
|
0.080 | Biomarker | disease | LHGDN | Stimulation of c-Myc transcriptional activity by vIRF-3 of Kaposi sarcoma-associated herpesvirus. | 17728244 | 2007 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | STR-428 represents a unique, B-cell lymphoma cell line carrying concurrent rearrangement of BCL2 and c-MYC genes with features distinct from those of HHV-8-related primary effusion lymphoma. | 17368758 | 2007 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The present case demonstrated a rare category of PEL that is not associated with HHV-8 or C-MYC gene rearrangement. | 15588855 | 2005 | ||||
|
0.080 | Biomarker | disease | BEFREE | These findings suggest that there may be an additional subcategory of primary effusion lymphoma that is not associated with HHV8 nor c-MYC(R) but is pathogenetically associated with the PAX-5 gene or hepatitis C virus. | 9850179 | 1998 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The PELs share several features with acquired immunodeficiency syndrome (AIDS)-associated primary central nervous system lymphomas (1 degree CNS-L), including B-cell phenotype, infection with Epstein-Barr virus, and lack of c-myc gene rearrangements. | 9484350 | 1998 |