Gene: CDR3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8163
Gene Symbol: CDR3
CDR3 		0.060 GeneticVariation disease BEFREE To gain insight into the mechanisms underlying VH CDR3 restrictions and also determine the developmental stage when restrictions in VH CDR3 are imposed, we analyzed partial IGHD-IGHJ rearrangements (D-J) in 829 CLL cases and compared the productively rearranged D-J joints (that is, in-frame junctions without junctional stop codons) to (a) the productive immunoglobulin heavy variable (IGHV )-IGHD-IGHJ rearrangements (V-D-J) from the same cases and (b) 174 D-J rearrangements from 160 precursor B-cell acute lymphoblastic leukemia cases (pre-B acute lymphoblastic leukemia [ALL]). 21968789 2012
Entrez Id: 8163
Gene Symbol: CDR3
CDR3 		0.060 Biomarker disease BEFREE T cell receptor (TCR) Vβ CDR3 repertoire diversity was analyzed in patients with chronic myeloid leukemia (CML) and BCR-ABL(+) B-cell acute lymphoblastic leukemia (B-ALL) by GeneScan. 21820025 2011
Entrez Id: 8163
Gene Symbol: CDR3
CDR3 		0.060 GeneticVariation disease BEFREE We analyzed the CDR3 region of 80 children with B-cell acute lymphoblastic leukemia (B-ALL) using the ImMunoGeneTics Information System and JOINSOLVER. 21649543 2011
Entrez Id: 8163
Gene Symbol: CDR3
CDR3 		0.060 Biomarker disease BEFREE Among these, CDR3 is considered unique for each lymphocyte and used as a tumour-specific marker in B-ALL patients. 15386562 2004
Entrez Id: 8163
Gene Symbol: CDR3
CDR3 		0.060 GeneticVariation disease BEFREE The tumor-specific V(H) CDR3 nucleotide sequence was successfully identified for all seven patients (3 mature B-ALL and BL). 14565664 2003
Entrez Id: 8163
Gene Symbol: CDR3
CDR3 		0.060 Biomarker disease BEFREE We analyzed the CDR-III sequences of B cell precursor acute lymphoblastic leukemia (pre-B ALL) cells in 23 newly diagnosed and 10 relapsed patients, in order to elucidate the organization of CDR-III in B cell precursors. 1541668 1992