Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.060 AlteredExpression disease BEFREE Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses. 24354892 2014
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.060 Biomarker disease BEFREE In summary, methylation of SOCS1, SOCS2, SOCS3 and CISH is infrequent in Ph-ve MPN. 24131863 2014
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.060 AlteredExpression disease BEFREE Furthermore, curcumin increased the transcript levels of SOCS1 and SOCS3 and significantly inhibited the clonogenic activity of hematopoietic progenitors from patients with MPNs. 23430957 2013
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.060 GeneticVariation disease BEFREE Interestingly, the SOCS3(F136L) mutation was detected in a Japanese myeloproliferative disorder patient cohort at double the frequency of healthy controls. 19735488 2010
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.060 PosttranslationalModification disease BEFREE The frequent inactivation of SOCS3 is a novel finding in CMPD with potential implications for the molecular pathology of these disorders. 18318760 2008
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.060 PosttranslationalModification disease BEFREE Hypermethylation of the SOCS3 promoter was identified in 16 of 50 (32%) patients with idiopathic myelofibrosis but not in patients with essential thrombocythemia, polycythemia vera or myelofibrosis preceded by another myeloproliferative disorder. 18815196 2008