| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | For example, recent data suggest that programmed cell death 1 blockade may lead to increased lymphoma growth. | 31672704 | 2020 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The clinical roles of PD-1/PD-L1 expression vary between subtypes of lymphoma. | 31704289 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | However, there is no evidence-based systematic review on the safety and efficacy of anti-PD-1 antibody in treating lymphoma. | 31118893 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Hence, the inclusion of a Dap10 or CD28 co-stimulatory domain in the chPD1 receptor was compared to determine which domain induced optimal anti-tumour immunity in a mouse model of lymphoma. | 28670716 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Herein, we systematically review the published literature on the expression and prognostic value of programmed cell death-ligand 1/programmed cell death-1 in these patients and identify considerable differences in expression patterns, distribution and numbers of programmed cell death-ligand 1<sup>+</sup>/programmed cell death-1<sup>+</sup>cells, both between and within lymphoma subtypes, which is reflected in conflicting findings regarding the prognostic value of programmed cell death-ligand 1<sup>+</sup>/programmed cell death-1<sup>+</sup> cells. | 27694502 | 2016 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma. | 27564404 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | Programmed cell death-1 inhibition in lymphoma. | 25943068 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Recent data have shown that cells within the immune microenvironment in lymphoma express programmed death ligand-1 (PD-L1) and many of the intratumoral T cells with an exhausted immune phenotype express programmed cell death-1 (PD-1). | 26049755 | 2015 |