Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 GeneticVariation disease BEFREE Classical Hodgkin lymphoma (cHL) and ALK- anaplastic large cell lymphoma (ALCL) share many morphologic and immunohistochemical features, causing difficulties in differential diagnosis. 30339972 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE Furthermore, we demonstrate there are similarities and differences in c-Jun and JunB function between cHL and ALK+ ALCL. 30375407 2018
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE These results add extra insights into the biological distinction between ALK+ ALCL and HL cells and highlight the Golgi apparatus as a target for the treatment of ALK+ ALCL. 26105086 2015
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE Difficulties with classification of lymphomas are also encountered, such as the distinction of classical Hodgkin's lymphoma from anaplastic large-cell lymphoma that is negative for anaplastic lymphoma kinase. 20227918 2010
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE Surprisingly, few genes are differentially expressed between systemic and cALCL despite their different clinical behaviour, and between ALK(-) ALCL and cHL despite their different cellular origin. 19657361 2009
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE Cases submitted as ALK- ALCL emphasized the immunohistochemical overlap with classical Hodgkin lymphoma (eg, CD15+/CD30+). 17511113 2007
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE Thus, analysing the neoplastic cells concurrently with their microenvironment, ALK-negative ALCL and ALCL-like HL seem to be related to each other, while cHL constitutes a separate lymphoma entity. 16874743 2006
Entrez Id: 238
Gene Symbol: ALK
ALK
0.080 Biomarker disease BEFREE Using the SSH technique, we compared the transcriptome of 2 cases of ALK+ and ALK- anaplastic large cell lymphoma (ALCL) and of 2 cases of classical Hodgkin's lymphoma (cHL) with opposite behavior. 15370244 2004