Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.030 | Biomarker | disease | BEFREE | A decision-analytic model was developed to evaluate the relative cost-effectiveness of reflex testing strategies for identifying Lynch syndrome in women with endometrial cancer taking the NHS perspective and a lifetime horizon. | 31469860 | 2019 | ||||
|
0.030 | GeneticVariation | disease | BEFREE | To investigate whether testing for LS in CRC patients using MSI or IHC (with or without <i>MLH1</i> promoter methylation testing and <i>BRAF</i> V600E testing) is clinically effective (in terms of identifying Lynch syndrome and improving outcomes for patients) and represents a cost-effective use of NHS resources. | 28895526 | 2017 | ||||
|
0.030 | GeneticVariation | disease | BEFREE | The objective of this project was to estimate the cost-utility of strategies to identify Lynch syndrome in individuals with early-onset colorectal cancer in the NHS. | 25910169 | 2015 |